This holder is very often used in laboratories for particle removal and for sterile filtration of several liters of volume. It has a stable construction and is easy to operate. The large filtration area of 130 cm2 ensures a high flow rate for the total filter volume. The supplied unscrewable hose nipples can be replaced by G3/8 connectors, if systems with particularly practical handling are required. The holder is designed for effective sterilization by autoclaving. The arrangement of the air-venting valve in the top plate and the test valve in the base plate ensures the necessary vapor penetration. The back pressure screen has a smooth surface in order to avoid damages to the membrane filters, and also when glass fiber prefilters are used. The swing-out locking clamps ensure a firm sealing simply by hand-tightening.