StreamLink® CC 15
Automated, High Throughput Solution for Efficient Sample Preparation of mAb-Expressing Cell Cultures
High throughput:
Clarification and/or purification of 24-48 × 5-15 mL culture samples in as little as 2 hours.
All-in-one system:
Controlled and simplified, reproducible streamlined clarification and purification process in one step.
Automation:
Automated walk-away process with integrated error recoveries to save time and reduced FTE (Full Time Equivalent).
- Catalog No.:
- 061-8B01
*Custom/bulk order quotes are provided within 72 hours of request.
Cell line, and early process development using Ambr® 15 produces between 24 – 48 parallel cell line cultivations of 5-15 mL samples. Preparing these samples for CQA analysis is a multi-step, labor-intensive and error-prone process that drains resources.
StreamLink® CC 15 is the first automated high throughput system that streamlines the preparation of 5-15 mL mAb cell culture samples. The one-step clarification and purification process accelerates and simplifies sample prep while maintaining quality through automated, optimized protocols.
Applications
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Application
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Cell Line Development
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Clarification
- Purification
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Cell Line Development
Dimensions
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Dimensions WxDxH530 × 1,220 × 660 mm
Operating Conditions
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Maximum Operating Pressure4 bar | 58 psi
Product Information
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BrandStreamLink®
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PackagingBox on pallet
Storage bottles with labels and plain lids for usewith the liquid handler
pH probe assembly
Aluminium lids for use with the storage bottles
Feed connection tubing set
Labware holder: Ambr®15 vessel holder with lid (holds 12x Ambr®15 vessels)
Glass bottle set for feed and waste with plain lids and labels
Lids for glass bottles with tubing assemblies and breathers and waste waste bottle lid with three tubing assemblies for connection.
Labware holder: 15 mL centrifuge tube holder with lid (holds 24x tubes)
Labware holder for microplates
Platform enabling a system to be set up on a surface that is not flat and | or level
Additional labware: Lid for centrifuge tube holder
Additional labware: Lid for Ambr®15 vessel holder
Labware holder: 50 mL centrifuge tube holder with lid (holds 12x tubes)
Custom bottle and tube set
Ambr® 15 Cell Culture microbioreactors with sparge
Sartobind® Rapid A is provided as ready-to-use devices which will be fully utilized within a single batch and afterwards disposed:
- >150 g/L*h productivity
- >30 g/L DBC 10% at 12 sec RT
- Average cycle times of only 10-15 min
Sartobind® Rapid A Nano 1.2 mL have been developed for working with small sample volumes while retaining the cylindrical design of large scale membrane adsorbers. They are perfect for small scale applications, such as screening or process development. The Nano is the smallest scalable product size within the Sartobind® product portfolio. Scalability is given for breakthrough curves, elution peak profile and flow rate.
Sartobind® Rapid A Nano 1.2 mL have been developed for working with small sample volumes while retaining the cylindrical design of large scale membrane adsorbers. They are perfect for small scale applications, such as screening or process development. The Nano is the smallest scalable product size within the Sartobind® product portfolio. Scalability is given for breakthrough curves, elution peak profile and flow rate.
Single-use multi-layer depth filter for optimum clarification (i.e. no centrifugation needed). The filter is sized for 5-15 mL input culture and provides > 90% product recovery. Suited for use in StreamLink® CC 15.