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Centrisart I | Centrifugal Ultrafiltration

Centrisart® I is a ready-to-use unit for small volume centrifugal ultrafiltration to separate proteins from low molecular weight substances in biological samples. Centrisart® I features a unique design: Ultrafiltration in the direction opposite to the centrifugal force. This is so effective in preventing premature blockage of the filter that even whole blood samples can be deproteinized. Centrisart® I can be used in fixed-angle or swinging-bucket rotors accepting standard 15 ml tubes. Ultrafiltration of 90% of the original sample volume is typically completed in about 30 min.The ultrafiltrate is collected in the floater insert tube, where it is readily accessible without removing the tube. Removal of proteins from biological samples is a critical step for e.g. drug binding studies or the determination of metabolites in serum.

  • Centrifugal ultrafiltration against direction of centrifugal force
  • Removal of proteins from biological samples, even whole blood
  • Fast and simple preparation of protein-free ultrafiltrates
  • Wide range of MWCO

Typical applications include

  • Drug binding studies
  • Determination of metabolites in serum
  • Protein removal from blood samples

Performance Characteristics

Time to filter
50% of sample
volume
Time to filter
90% of sample
volume
Passage of
sample
species
volume
BSA 1.0 mg/ml (66,000 MW)
5,000 MWCO 300 min. n/a 0 %
10,000 MWCO 35 min. 80 min. 2 %
20,000 MWCO 9 min. 20 min. 2 %
IgG 0.25 mg/ml (160,000 MW)
100,000 MWCO 13 min. 35 min. 3 %
Blue Dextran 0.1 mg/ml (2,000,000 MW)
300,000 MWCO 9 min. 25 min. 28 %

Choose your product

Products (6)

Centrisart® I Centrifugal Ultrafiltration Devices - 20 kDa MWCO (CTA)
MWCO
20 kD
Membrane Material
Cellulose Triacetate (CTA)
Centrisart® I Centrifugal Ultrafiltration Devices - 300 kDa MWCO (PES)
MWCO
300 kD
Membrane Material
Polyethersulfone (PES)
Centrisart® I Centrifugal Ultrafiltration Devices - Starter Pack
MWCO
5 – 100 kD
Membrane Material
Polyethersulfone (PES), Cellulose Triacetate (CTA)
Centrisart® I Centrifugal Ultrafiltration Devices - 100 kDa MWCO (PES)
MWCO
100 kD
Membrane Material
Polyethersulfone (PES)
Centrisart® I Centrifugal Ultrafiltration Devices - 5 kDa MWCO (CTA)
MWCO
5 kD
Membrane Material
Cellulose Triacetate (CTA)

Centrisart® I is a ready-to-use unit for small volume centrifugal ultrafiltration to separate proteins from low molecular weight substances in biological samples. Centrisart® I features a unique design: Ultrafiltration in the direction opposite to the centrifugal force. This is so effective in preventing premature blockage of the filter that even whole blood samples can be deproteinized. Centrisart® I can be used in fixed-angle or swinging-bucket rotors accepting standard 15 ml tubes. Ultrafiltration of 90% of the original sample volume is typically completed in about 30 min.The ultrafiltrate is collected in the floater insert tube, where it is readily accessible without removing the tube. Removal of proteins from biological samples is a critical step for e.g. drug binding studies or the determination of metabolites in serum.

  • Centrifugal ultrafiltration against direction of centrifugal force
  • Removal of proteins from biological samples, even whole blood
  • Fast and simple preparation of protein-free ultrafiltrates
  • Wide range of MWCO

Typical applications include

  • Drug binding studies
  • Determination of metabolites in serum
  • Protein removal from blood samples

Performance Characteristics

Time to filter
50% of sample
volume
Time to filter
90% of sample
volume
Passage of
sample
species
volume
BSA 1.0 mg/ml (66,000 MW)
5,000 MWCO 300 min. n/a 0 %
10,000 MWCO 35 min. 80 min. 2 %
20,000 MWCO 9 min. 20 min. 2 %
IgG 0.25 mg/ml (160,000 MW)
100,000 MWCO 13 min. 35 min. 3 %
Blue Dextran 0.1 mg/ml (2,000,000 MW)
300,000 MWCO 9 min. 25 min. 28 %

Application Note

High Recovery of Cationised Protein in Centrisart® I
en 178.4 kB

Brochure

Ultrafiltration Family
en 1.6 MB
宣传手册:实验室过滤产品精简目录
zh 19.0 MB

Catalog

Laboratory Filtration Products (US and Canada)
en 9.6 MB

User Manual

Centrisart® I
en 301.5 kB

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