Disposable capsules with ion exchange membranes for polishing in biomanufacturing.

Item No.: 
92MU0142DD-11

*Custom/bulk order quotes are provided within 72 hours of request.

Sartobind® capsules are especially suited for the removal of DNA, viruses and protein contaminants in biopharmaceutical production. Sartobind® membranes contain homogenously grafted binding sites on a reinforced cross-linked cellulose matrix. The large pores (>3 um) increase the process speed and avoid diffusion limits compared to conventional bead chromatography. Membrane adsorbers feature extremely short cycle times and provide exceptionally high flow rates and throughput. A large product portfolio of Sartobind® capsules help to introduce an economical solution to production without validation.

  • Simple handling
  • High speed polishing
  • Less buffer consumption
  • Disposable and ready-to-use

Applications

  • Application
    • Capturing  
    • Polishing  

Connections (Physical)

  • Connectors
    Female Luer lock  

Dimensions

  • Bed Height
    4 mm  
  • Dimensions WxDxH
    31 × 11 cm  
  • Membrane Area
    2.9 cm²  

Features

  • Reusable
    No  

General Specifications

  • Filter Format
    Capsules  
  • Flow Rate
    0.8 – 2.4 mL/min  

Materials of Construction

  • Housing Material
    Polypropylene (PP)  
  • Materials of Construction
    Polypropylene, polyester  
  • Membrane
    • Strong anion exchanger  
    • Strong cation exchanger  
    • Salt tolerant anion exchanger  
  • Membrane Material
    Stabilized reinforced cellulose  

Operating Conditions

  • Maximum Operating Pressure
    0.6 MPa  
  • Maximum Venting Pressure
    0.5 bar, 0.05 MPa, 7 psi  
  • pH Stability
    Q, PA: 2 – 14 (short term), S: 3 – 14 (short term)  

Physicochemical Information

  • Bed Volume
    0.08 mL  
  • Ligand
    • Quaternary ammonium  
    • Sulfonic acid  
    • Primary amine (PA)  
  • Ligand Density
    Q, S: 2 – 5 µeq/cm², PA: 18 – 22 µeq/cm²  
  • Pore Size Final-filter
    3 – 5 µm  
  • Reference Protein
    • Bovine serum albumin (BSA)  
    • Lysozyme  
  • Thermal Stability
    Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.  
  • Void Volume
    0.4 mL  

Product Information

  • Brand
    Sartobind® pico  
  • Pack Size
    One each of Q, S and STIC PA  
  • Type
    Membrane adsorber  
  • What you receive
    • One each of Q  
    • S and STIC PA  
    • 1 operating instruction  
  • Sartobind® Adapter UNF 10-32 female to Luer male

    Adapter UNF 10-32 female to Luer male for Sartobind®Material: natural PEEK