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Sartobind® Selection Kit pico

Disposable capsules with ion exchange membranes for polishing in biomanufacturing.

Item no.:  92MU0142DD-11

Sartobind® capsules are especially suited for the removal of DNA, viruses and protein contaminants in biopharmaceutical production. Sartobind® membranes contain homogenously grafted binding sites on a reinforced cross-linked cellulose matrix. The large pores (>3 um) increase the process speed and avoid diffusion limits compared to conventional bead chromatography. Membrane adsorbers feature extremely short cycle times and provide exceptionally high flow rates and throughput. A large product portfolio of Sartobind® capsules help to introduce an economical solution to production without validation.

  • Simple handling
  • High speed polishing
  • Less buffer consumption
  • Disposable and ready-to-use

Application Note

Using the Sartobind® pico — Optimizing Steps for using micro-scale membrane adsorbers on liquid chromatography systems
en 1.5 MB

Datasheet

Sartobind® pico 0.08 mL — Membrane chromatography tool for process development
en 231.9 kB

User Manual

Sartobind® Selection Kit — pico 0.08 mL with Q, S and STIC PA membranes — A Separation Technology Based on Macroporous Membranes, 4 mm Bed Height
en 396.6 kB

Applications

  • Application
    • Capturing
    • Polishing

Biological Information

  • Reference Protein
    Q, PA: Bovine serum albumin, S: Hen egg white lysozyme

Connections (Physical)

  • Connectors
    Luer female connectors

Dimensions

  • Bed Height
    4 mm
  • Dimensions (W×D×H)
    31 × 11 cm
  • Membrane Area
    2.9 cm²

Features

  • Reusable
    No

Materials of Construction

  • Housing Material
    Polypropylene (PP)
  • Materials of Construction
    Polypropylene, polyester
  • Membrane
    Strong anion exchanger, Strong cation exchanger, Salt tolerant anion exchanger
  • Membrane Material
    Stabilised reinforced cellulose

Operating Conditions

  • Maximum Operating Pressure
    0.6 MPa
  • Maximum Venting Pressure
    0.5 bar, 0.05 MPa, 7 psi
  • Thermal Stability
    Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.

Physicochemical Information

  • Chemical Compatibility
    Stable in common chromatography buffers, unstable to peroxide and other oxidizing or reactive reagents
  • Ligand Density
    Q, S: 2 – 5 µeq/cm², PA: 18 – 22 µeq/cm²
  • Pore Size Final-filter
    3 – 5 µm

Product Information

  • Membrane Type
    Strong anion exchanger, Strong cation exchanger, Salt tolerant anion exchanger
  • Pack Size
    One each of Q, S and STIC PA
  • Primary Product Type
    Membranes
  • Type
    Membrane adsorber
  • What you receive
    • One each of Q
    • S and STIC PA
    • 1 operating instruction

Specifications

  • Filter Format
    Capsules
  • Flow Rate
    0.8 – 2.4 mL/min
  • Ligand
    Quaternary ammonium, Sulfonic acid, Primary amine (PA)
  • pH Stability
    Q, PA: 2 – 14 (short term), S: 3 – 14 (short term)

Volumes

  • Bed Volume
    0.08 mL
  • Void Volume
    0.4 mL