Serum free and Feeds
Serum-free media formulations must satisfy a number of nutritional and physical requirements of cells that are normally addressed by the presence of serum. Serum proteins, such as albumin, fibronectin, and fetuin serve a variety of functions that include adsorbing toxic compounds, providing protection against shear forces in bioreactors, creating a matrix for cellular attachment to surfaces, and acting as a carrier for lipids and other growth factors.
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