Celsius® S3 Benchtop System EU

The Celsius® S3 Benchtop System is a laboratory instrument made to evaluate freeze & thaw processes of new drug candidates in single-use bags with full scalability to production-scale Celsius® platforms (FFT, FFTp and CFT).

Catalog No.: 
FTH-CS00000-0002
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

The Celsius® S3 Benchtop System is the only lab-scale freeze & thaw system in single-use bags that is scalable to our production-scale Celsius® platforms (FFT, FFTp and CFT). This system is a tool to execute freeze & thaw process development and stability studies using a minimal amount of product.

Scalability

The Celsius® S3 Benchtop System models production system with a minimal amount of product. Using the same freeze & thaw critical process parameters and identical materials of construction in all Celsius® Pak, the Celsius® S3 Benchtop System ensures unmatched scalability between all scale systems.

Ease of Use

The CryoPilot Control Unit provides automated operation and data collection. The Celsius® S3 Benchtop System freezes and thaws from 1 to 10 product samples per run. Lab-scale Celsius® Pak PDS are available in sizes of 30 mL and 100 mL nominal fill volume with different filling port and thermowell configurations.

Improved Process Validation

Celsius® S3 Benchtop System offers excellent batch to batch reproducibility and consistent product stability after freezing, thawing and storing. The Celsius® S3 Benchtop System provides documented and reproducible freeze & thaw processes, thus facilitating validation of your freeze and thaw operations.

Celsius® S3 Benchtop System Applications:

  • Process development studies to understand decoupling (hold) steps during downstream processing, i.e., frozen storage of process intermediates, frozen storage of drug substances. Investigate the Celsius® technology for future scale-up. (FFT, FFTp and CFT)
  • Scale-down storage and transportation studies (using minimal volumes as low as 20 mL) for understanding extended drug substance storage (time and temperature) and shipping
  • Formulation development of freeze & thaw compatible formulations for drug substance
  • Stability Studies in accordance to industry guidelines, conducted in freezing and thawing conditions as well as in a container closure system that is the same as or simulates the packaging proposed for freezing, storage, shipping and thawing at production-scale

Accessories Information

  • Software
    Cryopilot® 5

Applications

  • Application Area
    Frozen Storage & Shipping
  • Process Step
    • Cell Harvest & Downstream Processing Intermediates
    • Drug Substance Purification
    • Drug Product Formulation
    • Lab-scale Freeze & Thaw

Dimensions

  • Dimensions WxDxH
    1880 x 760 x 710 mm

Features

  • Languages
    English
  • Load Capacity
    10× Lab-scale Celsius® Pak

General Specifications

  • Additional Product Specifications
    Control unit: Laptop computer
  • Temperature Range
    -60°C – +40°C

Materials of Construction

  • Materials of Construction
    • 302/304 Stainless Steel
    • 6061-T6 aluminum
    • 5052 aluminum
    • transparent PVC cover

Power Requirements

  • Power Plug
    European Union
  • Power Requirements
    230 V, 50 Hz, 16 A breaker minimum, 1 Phase

Product Information

  • Brand
    Celsius® S³
  • Freezer Technology
    Lab-scale freezing

Volumes

  • Working Volume
    20 mL – 1 L
Lab-scale Celsius® Pak 30mL (LL/LL)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 100mL (MPC/MPC)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 30mL (LL/LL/EVA)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 100mL (LL/LL)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 100mL (MPC/MPC)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 100mL (LL/LL)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 30mL (MPC/MPC)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 30mL (LL/LL)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 30mL (MPC/MPC)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

Lab-scale Celsius® Pak 100mL (LL/LL)

Celsius® Lab-scale implements small-scale single-use Celsius® solutions to support production-scale freezing and thawing operations with the Celsius® technology.

Scalability is a feature unique to Celsius® . Lab-scale Celsius® Paks together with the process development tool called Celsius® S3 Benchtop System allow you to characterize the freeze & thaw processes on your biopharmaceutical product in the lab before scaling-up to the production system.

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