Sartocon® PESU Cassette
Polyethersulfone membranes (PESU) are stable polymer that feature a broad pH and temperature range. Polyethersulfone ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:
- 1 kD
- 5 kD
- 8 kD
- 10 kD
- 30 kD
- 50 kD
- 100 kD
- 300 kD
Item no.: 3021465935E-BSW
PESU Polyethersulfone membranes are membrane polymers that are well established in the biotechnological and pharmaceutical industries. The PESU membrane is a stable polymer that features a broad pH and temperature range. Its wide temperature range makes it possible to sterilize the membrane by either steam or autoclaving. Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures. Because of these features, the PESU membrane is ideally suited for biotechnological applications. PESU cassettes are available in 0.1 µm. Polyethersulfone membranes are designed for applications in the biotechnological and pharmaceutical industries.
They can be used to remove the following cells from liquids:
- Mammalian cells
- Mycoplasma reduction
Polyethersulfone can withstand in-line steam sterilization without any loss of integrity or changes in membrane retention. Membrane retention is unaffected by re-use.
IndustryPharma / Biotech
Bacterial Endotoxins< 0.18 EU/mL as determined by the LAL test
BiosafetyAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Filtration Area3.5 m²
Flow Channel GeometryProtein conc. >20% /or viscosity above.3cp
Cassette FormatSartocube Cassettes
Filter ConfigurationSartocube Cassette
Ultrafilter30 kD Polyethersulfone Ultrafilter Membrane
Materials of Construction
Integral FramePolyvinylidene fluoride (PVDF)
Membrane MaterialPolyethersulfone (PES)
Sealing CompoundSilicone White (High chemical resistance)
Maximum Inlet Pressure4 bar
pH StabilitypH 2 – 14
Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Filter TypeCrossflow Filters
The Sartoflow® 20 stainless steel holder with hydraulic is designed for crossflow applications from 200 l to 2500 l volumes. The holder is optimized for use with 4 Sartocon® up to 20 Sartocube® production scale crossflow cassettes (max. 14 m2). Typical applications of the Sartoflow® 20 system includes concentration and diafiltration of proteins, vaccines, antibodies, oligo nucleotides, endotoxin removal etc., cell harvesting and clarification processes.