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Sartocon® Hydrosart® Cassette

Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications.

  • Hydrosart® is stable across a broad pH range.
  • Hydrosart® is extremely hydrophilic, making it non-protein binding, and virtually non-fouling.
  • Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations.

These features make Hydrosart® an ideal membrane for biological applications.

Item no.:  3021860706W--SW

Availability:  On Request

   

Hydrosart® is a stabilized cellulose derivative membrane polymer that has been optimized for the biotechnological and pharmaceutical industries. The Hydrosart® membrane is a stable polymer that features a broad pH and temperature range. Hydrosart is also extremely hydrophilic, making it non-protein binding and virtually non-fouling. As a result, it has extremely high flux. Hydrosart®’s wide temperature range makes it possible to sterilize the membrane by either steam or autoclaving. Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures. Hydrosart® membranes are designed for use in the biotechnological and pharmaceutical industries.

They can be used to remove the following from liquids:

  • Mammalian cells: CHO BHK

  • Bacteria: E. coli Pasteurella C. diphtheria

  • Yeasts

  • Cell Iysates Product

Hydrosart® has minimal adsorption of proteins, viruses, etc. Membrane retention is unaffected by repeated re-use. Hydrosart® has been validated to withstand in-line steam sterilization without any loss of integrity or changes in membrane retention.

Datasheet

Hydrosart® Microfiltration Cassettes — Cell harvest and bacteria concentration
en 324.9 kB

Compliance Information

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test
  • Biosafety
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filtration Area
    0.6 m²
  • Flow Channel Geometry
    Microfilter Wide Spacer

General Specifications

  • Cassette Format
    Sartocon Cassettes
  • Filter Class
    Microfilter
  • Filter Format
    Cassettes

Operating Conditions

  • Maximum Inlet Pressure
    4 bar
  • pH Stability
    pH 2 – 14

eShop Dynamic Attributes

  • Filter Type
    Crossflow Filters
  • Industry
    Pharma / Biotech
  • Integral Frame
    Polyvinylidene fluoride (PVDF)
  • Membrane Material
    Hydrosart®
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
  • Pore Size
    0.2 µm
  • Sealing Compound
    Silicone White (High chemical resistance)
  • Spacer
    Polypropylene (PP)