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Ambr® Crossflow - 8 channel system including control station

Study factors for manufacturability

Collect important information about the behaviour of the molecules in downstream processing already in an early stage

Automated, parallel trials

Up to 16 channels can be managed by one control station

Lowest process volumes

Small scale screening with 10 cm² membrane area | 5 mL recirculation volume

Item no.:  061-8A61

   

Ambr® Crossflow provides at early development stages access to molecule behavior under challaging DSP specially UF/DF conditions.

Ambr® Crossflow is a benchtop crossflow system optimised for ultrafiltration and diafiltration applications. It is a small-scale screening system with a minimum recirculation volume of 5 mL and a dedicated new range of Ambr® CF Filter cassettes with 10 cm² membrane area. Parallel operation is achieved with 4 independent crossflow channels per module, with up to 4 modules managed by one control station. This means Ambr® Crossflow is capable of performing membrane screenings with up to 16 Ambr® CF Filters simultaneously.

Intuitive hardware and software design ensures that the system is quick to set up and easy to use, while full system automation ensures reliable process control and reduced manual intervention.

Learn more at www.sartorius.com/ambr-crossflow

Application Note

Qualification of an Automated, High Throughput Crossflow System as a Scale-Down Model for Ultrafiltration and Diafiltration Process Development
en 1.2 MB
Applications of an Automated High Throughput Crossflow System for Ultrafiltration Process Development to Assess Manufacturability of Monoclonal Antibodies
en 1.3 MB
Evaluation of an Automated High Throughput Crossflow System as a Small-Scale Model of Bench Top Crossflow Filtration in Formulation Studies of Monoclonal Antibodies
en 367.2 kB
Optimizing diafiltration parameters for maximum recovery of a bispecific antibody using low process volumes and an automated high throughput crossflow system
en 233.2 kB
Optimization of EnPCs® Purification With Ambr® Crossflow and MODDE®
en 11.7 MB

Datasheet

Ambr® Crossflow The High Throughput Solution for Parallel Screening
en 1.3 MB

General Specifications

  • Channels
    8
  • Pump Output
    0 – 50 mL/min

Operating Conditions

  • Maximum Operating Pressure
    3 bar (43.5 psi)
  • Minimum Operating Volume
    5 mL

Volumes

  • Recirculation Vessel Volume
    120 mL

eShop Dynamic Attributes

  • Including Control Station
    Yes
  • Recirculation Vessel
    Polystyrene (PS)
Ambr® CF Filter, Polyethersulfone 100 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter, Polyethersulfone 10 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter  Hydrosart®, 5 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

ambr® CF Filter  Hydrosart® 10 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® crossflow system.

Ambr® CF Filter, Polyethersulfone 30 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter  Hydrosart®, 100 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter  Hydrosart®, 30 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® crossflow system.

Ambr® CF Filter, Polyethersulfone 5 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.