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Biostat STR® Generation 3

Biostat STR® single-use bioreactors running on the Biobrain® automation platform offer multiple configurations and convenient software upgrades to quickly adapt facilities as requirements change. The generation 3 system is now available with integrated Repligen XCell ATF® Technology for intensified processes and access to our best-in-class BioPAT® toolbox. Biostat STR® bioreactors and Flexsafe STR® bags range from 50 L to 2,000 L and can enhance speed, quality, and flexibility in process development and commercial manufacturing operations.

Item no.:  BIOSTATSTR3-R2


Engineered for Ultimate Upstream Performance

Maximize Your Quality and Consistency

The Biostat STR®

Single-Use Bioreactor System is engineered for ultimate upstream performance delivering quality and precision while at the same time adapting to changing process requirements with maximum flexibility. In addition to the standard features, you can incorporate advanced options such as integrated XCell ATF®Technology

BioPAT® process control tools and software, and sophisticated analytics. Biostat STR® delivers:  

  • Superior cell viability and density 
  • Higher product purity 
  • Lower risk of batch loss or inconsistencies 
  • Improved process understanding, control, and productivity 
  • Systematic cost savings at all lifecycle phases of drug production 
  • Working volumes from 12.5 L to 2,000 L
  • Highly efficient mixing and high oxygen transfer
  • Improved process understanding, control, and productivity 
  • From mAbs and biosimilars to pDNA, mRNA, and vaccines, the Biostat STR® 3 suits numerous modalities

Build a fully flexible, modular seed train

The Biostat STR® 3 serves all process strategies, from classical batch to intensified processes, and covers all stages of the seed train up to the final production bioreactor with its working volume range from 12.5 L to 2,000L.

  • Modular design with interchangeable bagholder allows for maximum flexibility
  • Process intensification ready through integrated XCell ATF® technology
  • Complemented by Biostat® RM rocking motion bioreactors in a wealth of seed train scenarios


Biostat STR® Generation 3 and Biobrain® Automation Platform - Commercial Manufacturing
en 888.1 kB
Biostat STR® Generation 3 and Biobrain® Automation Platform - Process Development
en 704.2 kB


  • Application
    • Cell Culture
    • Cell Culture (recombinant proteins, mAbs)
    • Cell Culture (Vaccine)
    • Cell Therapy
    • GMP Compliance
    • mAB Production
    • Recombinant Protein Production
    • Vaccine Production
  • Process Step
    • Clinical Trial Manufacturing
    • Commercial Manufacturing
    • Process Development
    • Pilot
  • Scale
    • Commercial manufacturing
    • Pilot
    • Process
    • Product development

Compliance Information

  • IP Protection Class
    • Control Tower: IP65 / NEMA 4x
    • Bagholder: IP54 / NEMA 12
  • Quality Standards
    • GAMP 5
    • ISA 88
    • OPC-UA


  • Sensors
    • BioPAT® Viamass
    • BioPAT® Trace
    • Optical DO
    • Optical pH
    • pH, DO
  • Temperature Sensor

Product Information

  • Brand
    Biostat® STR