Pilot Filter Holder — For Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers

Filter Holders are hydraulic clamping systems especially designed for the use of modular Sartoclear® Depth Filter cassettes and Sartobind® membrane chromatography cassettes. The holders are available in three standard formats for pilot scale and commercial manufacturing.

Item No.: 
2ZGL--0005
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

One platform for two technologies

Sartoclear® Depth Filters and Sartobind® membrane chromatography cassettes are two complementing technologies using the same holder and manifold plates. Use Sartoclear® Depth Filters for applications with moderate solids content. If you need large scale membrane chromatography for virus | VLP large protein capture use Sartobind® anion or cation exchangers cassettes. And to scale above 2000 L monoclonal antibody production for aggregate removal, Sartobind® Phenyl cassettes would be the right choice.

Easy handling

The filter holders are made for the use in a biopharmaceutical environment. The systems are designed for easy cleaning and ergonomic handling. The installation of varying numbers of filters is intuitive, fast and easy.

User friendly

The filter holders are equipped with easy accessible mounting bars for the quick and secure installation of commonly used accessories such as pressure sensors, pressure safety devices and bioburden reduction filters.

Applications

  • Application
    • Cell Harvest  
    • Polishing  

Dimensions

  • Dimensions WxDxH
    133 × 79 × 96 cm  

Product Information

  • Filter Holder Type
    Pilot Filter Holder  
  • Sartobind® Q Cassette 0.8 L with 4 mm bed height

    Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity.

    The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

  • Sartobind® S Cassette
    Item no.
    98IEXS42E-P

    Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

    The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

  • Sartobind® S Cassette
    Item no.
    98IEXS42D-L

    Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

    The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

  • Sartobind STIC® PA Cassette 0.8 L with 4 mm bed height

    Sartobind STIC® PA (primary amine) anion exchange membrane overcomes reduced binding capacity for host cell protein removal and can be used in high-salt conditions.

    The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

  • Sartobind Phenyl Cassette 1.6 L with 8 mm bed height

    Sartobind® Phenyl accomplishes polishing and capturing ten times faster than do conventional HIC resins. The membrane shows comparable, high binding capacity, without size exclusion effects, for proteins in a range of 20 mg mAb/mL membrane, as well as excellent resolution and impurity reduction.

  • Sartobind® Q Cassette 1.6 L with 8 mm bed height

    Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity.

    The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

  • Manifold Set Gamma for Sartobind® Cassettes

    The gamma irradiated (≥ 25 kGy, max.50 kGy) manifold set contains the inlet and outlet plates for Sartobind® Cassettes.

  • Manifold Set for Sartoclear® Depth Filters and Sartobind® Membrane Adsorbers

    The manifold set contains the inlet and outlet adapter plates for Sartoclear® Depth Filters as well as Sartobind® membrane adsorbers cassettes.

  • Sartoclear® Caps
    Item no.
    Sartoclear_Caps

    Clarification - Screening - High Throughput Depth Filter

    Sartoclear® Caps are easy-to-use, single-use screening devices designed to identify the optimal depth filter grade for your application.

    Filter Media: Cellulose + Diatomaceous Earth

    Effective Filtration Area: 25 cm²

    Connectors: 0.25 inch Multiple Stepped Hose Barb

    Packaging: 3 Pieces

  • Sartoclear® Cassettes 0.4 m²
    Item no.
    Sartoclear_Cassettes_0.4

    Clarification - Manufacturing - High Throughput Depth Filter

    Sartoclear® Cassettes with 0.4 m² filtration area offer a flexible and modular single-use apporach for seamless adaptation of different process volumes.

    Filter media: Cellulose + Diatomaceous Earth

    Effective Filtration Area: 0.4 m²

    Manifold Plate Connectors: 1.5 inch Sanitary Adapter

    Packaging: 1 Piece

  • Sartoclear® Cassettes 0.2 m²
    Item no.
    Sartoclear_Cassettes_0.2

    Clarification - Manufacturing - High Throughput Depth Filter

    Sartoclear® Cassettes with 0.2 m² filtration area offer a flexible and modular single-use apporach for seamless adaptation of different process volumes.

    Filter media: Cellulose + Diatomaceous Earth

    Effective Filtration Area: 0.2 m²

    Manifold Plate Connectors: 1.5 inch Sanitary Adapter

    Packaging: 1 Piece

  • Sartoclear® Midscale Cassettes
    Item no.
    Sartoclear_Midscale_Cassettes

    Clarification - Small Scale | Pilot - High Throughput Depth Filter

    Sartoclear® Midscale Filter Cassettes are single-use, self-conatining devices developed for scale-up depth filtrations with volumes between 5 and 10 liters.

    Filter media: Cellulose + Diatomaceous Earth

    Effective Filtration Area: 800 cm²

    Connectors: 0.75 inch Sanitary Adapter

    Packaging: 1 Piece

  • Sartoclear® Cassettes 0.8 m²
    Item no.
    Sartoclear_Cassettes_0.8

    Clarification - Manufacturing - High Throughput Depth Filter

    Sartoclear® Cassettes with 0.8 m² filtration area offer a flexible and modular single-use apporach for seamless adaptation of different process volumes.

    Filter media: Cellulose + Diatomaceous Earth

    Effective Filtration Area: 0.8 m²

    Manifold Plate Connectors: 1.5 inch Sanitary Adapter

    Packaging: 1 Piece

  • Sartoclear® Separation Plate

    For serial or parallel filtration on one layer

  • Drip pan for Pilot Filter Holder

    For easy cleaning of spilled fluids

  • Pressure Safety Device
    Item no.
    2ZGL--0014

    Prevents excessive pressure during compressed air draining of the filter cassettes.