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Sartobran® Cartridge 0.45µm

Sartobran® P

Sartobran® P with its unique low-binding cellulose acetate (CA) membrane is mainly used for the sterile filtration of blood & plasma products and vaccines. The ultra-low binding of the membrane material leads to highest product yield and exceptional filtration performance. Especially large, shear-stress sensitive proteins do not lose their structure and function when filtered through this special membrane. This will improve your product yield even further.

Order Number:  5232706D2----P

Availability:  On Request

Sterilizing-Grade, 0.2 µm Rated Filters
Sartobran® P Pore size: 0.45 | 0.2 µm (heterogeneous CA double layer)

Bioburden Reduction, 0.45 µm Rated Filters
Sartobran® P Pore size: 0.8 | 0.45 µm (heterogeneous CA double layer)

Your Benefits:

  • High product yield due to ultra-low unspecific adsorption
  • Excellent filtration results especially for large, shear-stress sensitive proteins
  • Exceptional total throughput especially for blood and plasma products

Sartobran® P filters are not suitable for gamma irradiation. Please check also Filter Transfer Sets for easy integration of non-gamma filters into single-use assemblies.
For highest process flexibility all Sartobran® P filters are available for conventional or single use applications. All filter elements are available in various sizes and adapter combinations. Please review the selection guide in the supporting resources literature.


Sartobran ® P 0,45 µm Cartridges & MidiCaps & MaxiCaps
en 575.5 kB

Product properties

  • Capsule/Cartridge Format
  • Filter Size
    20" (1.2 m² / 12.9 ft²)
  • Material prefilters
    Cellulose Acetate (CA)
  • Connector Outlet
    Bayonet Adapter with 222 Double O-ring (27)
  • Connector Inlet
    Bayonet Adapter with 222 Double O-ring (27)
  • Filtration area
    1.2 m² / 12.9 ft²
  • Height
    530 mm
  • Pore size pre-filter
    0.65 µm
  • Pore size final-filter
    0.45 µm
  • Outer diameter
    70 mm
  • Material o-ring | seal
    Silicone (SI)
  • Vent Valve

Technical attributes

  • Sterilization Procedures
    In-Line Steam Sterilization=== at 134 °C, 20 min., 0.5 bar, min. 25 Cycles` Autoclaving=== at 134°C, 30 min, 2 bar, min. 25 Cycles
  • Industry
  • Sterilization Method
    Autoclavable & In-Line Steam Sterilizable
  • Bacterial Endotoxins
    < 0.25 EU/mL as determined by the LAL test
  • GMP Compliance
    This product was manufactured in conformance with established Current Good Manufacturing Practice (cGMP) standards.
  • Maximum Differential Pressure
    20 °C=== 5 bar; 80 °C=== 2 bar
  • Biosafety
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
  • Housing material
    Polypropylene (PP)
  • Support Fleece
    Polypropylene (PP)
  • Min. required Bubble Point
    2.0 bar
  • Max. Allowable Back Pressure (at 20°C)
    2 bar / 29 psi at 20°C; 1 bar / 14.5 psi at 80°C
  • Max. diffusion
    30 mL/min at 1.5 bar | 22 psi
  • Application
    Blood and Plasma` Vaccine Production