Celsius® S3 Benchtop System
The Celsius® S3 Benchtop System is a laboratory instrument made to evaluate freeze & thaw processes of new drug candidates in single-use bags with full scalability to production-scale Celsius® platforms (FFT, FFTp and CFT).
*Custom/bulk order quotes are provided within 72 hours of request.
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The Celsius® S3 Benchtop System is the only lab-scale freeze & thaw system for single-use bags that is scalable to our production-scale Celsius® platforms (FFT, FFTp and CFT). This system is a tool to execute freeze & thaw process development and stability studies using a minimal amount of product.
Scalability
Using the same freeze & thaw critical process parameters and materials of construction as seen in all Celsius® Paks, the Celsius® S3 Benchtop System ensures unmatched scalability across systems of all scales.
Ease of Use
The CryoPilot Control Unit provides automated operation and data collection. The Celsius® S3 Benchtop System freezes and thaws 1 to 10 product samples per run. Lab-scale Celsius® Pak PDS are available in 30mL and 100mL nominal fill volumes with various filling port and thermowell configurations.
Improved Process Validation
The Celsius® S3 Benchtop System offers excellent batch-to-batch reproducibility as well as consistent product stability after freezing, thawing, and storing. The Celsius® S3 Benchtop System allows for documented and reproducible freeze & thaw processes, thus facilitating validation of your freeze & thaw operations.
Celsius® S3 Benchtop System Applications:
- Process development studies to understand decoupling (hold) steps during downstream processing, e.g., frozen storage of process intermediates or drug substances. Explore the Celsius® technology for future scale-up. (FFT, FFTp and CFT)
- Scale-down storage and transportation studies (using minimal volumes as low as 20mL) for understanding extended drug substance storage and shipping in terms of time and temperature
- Formulation development of freeze & thaw compatible formulations for drug substances
- Stability Studies in accordance with industry guidelines, conducted in freezing and thawing conditions as well as in a container closure system that is the same as or simulates the packaging proposed for freezing, storage, shipping, and thawing at production-scale
Application Note
Brochure
Datasheet
Flyer
Publication
Accessories Information
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SoftwareCryopilot® 5
Applications
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Application AreaFrozen Storage & Shipping
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Process Step
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Cell Harvest & Downstream Processing Intermediates
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Drug Substance Purification
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Drug Product Formulation
- Lab-scale Freeze & Thaw
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Cell Harvest & Downstream Processing Intermediates
Dimensions
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Dimensions WxDxH1880 x 760 x 710 mm
Features
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LanguagesEnglish
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Load Capacity10× Lab-scale Celsius® Pak
General Specifications
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Additional Product SpecificationsControl unit: Laptop computer
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Temperature Range-60°C – +40°C
Materials of Construction
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Materials of Construction
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302/304 Stainless Steel
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6061-T6 aluminum
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5052 aluminum
- transparent PVC cover
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302/304 Stainless Steel
Product Information
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BrandCelsius® S³
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Freezer TechnologyLab-scale freezing
Volumes
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Working Volume20 mL – 1 L
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.
Lab-scale Celsius® Paks, when combined with the Celsius® S3 Benchtop System, allow users to optimize their freeze & thaw processes in the lab before scaling-up to the production system.
These small-scale, single-use solutions simplify scalability when transitioning from lab work to production.