Virosart® HC Minisart®

The high capacity virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in blood & plasma applications.

Item No.: 
539VM----------B

*Custom/bulk order quotes are provided within 72 hours of request.

Tutorial

Virosart® HC & Virosart® CPV Minisart® Lab Scale Product Tutorial

Learn how to install and perform virus filtration. You will also receive recommendations on handling to improve the final filtration.

Watch Training Video

Application:

  • Virus clearance: Virosart® HC retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV).
  • Target molecule: The main applications for Virosart® HC for virus filtration are hydrophobic feed streams such as IVIG or any other plasma derivates as well as hydrophobic antibodies & recombinant proteins (< 150 kD).
  • Positioning: Virosart® HC is used towards the end of the purification process of biopharmaceutical products for the virus filtration. At this stage, the purity of the biopharmaceutical product is at its highest and so fouling of the filter by contaminants (DNA, CHOP, aggregates & lipoproteins) will be low.

Product Benefits:

  • Robust virus clearance: Virosart® HC retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV). This filter offers highest virus safety over the entire flow decay profile independently of operating pressure.
  • Smart process transfer: Flexibility is give by using either cartridges in existing stainless steel housings or disposable capsules.
  • Ease of use: Virosart® HC are tested for integrity using a water-based diffusion test, e.g. based on the Sartocheck® technology of Sartorius Stedim Biotech

Regulatory Compliance:

  • Validated for ≥ 4 LRV removal of small non-enveloped viruses using bacteriophage PP7
  • Designed, developed and manufactured in accordance with an
  • ISO 9001 certified Quality Management System
  • Meet or exceed the requirements for WFI quality standards set by the current USP
  • Non pyrogenic according to USP Bacterial Endotoxins
  • USP Plastic Class Test VI

Applications

  • Application
    Blood and Plasma  

Connections (Physical)

  • Connector Inlet
    Luer Lock  
  • Connector Outlet
    Luer Lock  

Dimensions

  • Filtration Area
    5 cm²  

Features

  • Integrity Tested
    No  

General Specifications

  • Capsule/Cartridge Format
    Down scale unit  
  • Filter Format
    Down Scale Units  

Materials of Construction

  • Filter Material
    Polyethersulfone (PES)  

Physicochemical Information

  • Pore Size
    20 nm (nominal)  

Product Information

  • Brand
    Virosart® HC  
  • Pack Size
    5  

Sterility/Purity

  • Delivery Condition
    Non sterile - Autoclavable  
  • Virosart® Max Sartolab
    Item no.
    54ASA----------V

    Maximize your virus filter performance with adsorptive pre-filtration. Virosart® Max is a specifically optimized virus pre-filter significantly increasing downstream virus filter performance.

  • Virosart® Max Minisart®
    Item no.
    54AMI----------B

    Maximize your virus filter performance with adsorptive pre-filtration. Virosart® Max is a specifically optimized virus pre-filter significantly increasing downstream virus filter performance.