Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

Item No.: 
99IEXS42GC-----D

*Custom/bulk order quotes are provided within 72 hours of request.

Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.

Applications:

The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).

Benefits:

The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.

  • High speed host cell protein removal up to 30 bed volumes/ min
  • Aggregate removal

Easy to use:

  • Plug and play devices from 0.08 ml to 5 l
  • Can be used like a filter
  • Flow rate up to 30 bed volumes/min
  • Disposable or re-usable

Applications

  • Application
    Screening  

Connections (Physical)

  • Connectors
    N/A  

Dimensions

  • Bed Height
    0.8 mm  
  • Dimensions WxDxH
    128 × 85.5 × 25 mm  
  • Membrane Area
    0.7 cm²  

Features

  • Reusable
    No  

Materials of Construction

  • Housing Material
    Polypropylene (PP)  
  • Material 8-strip
    Polypropylene (PP)  
  • Material Holding Frame
    Polystyrene  
  • Materials of Construction
    Polyester  
  • Membrane Material
    Stabilized reinforced cellulose  

Operating Conditions

  • Maximum Operating Pressure
    35 kPa  
  • pH Stability
    pH 3 – 14 (short term)  

Physicochemical Information

  • Bed Volume
    19 µL/well  
  • Ligand
    Sulfonic acid  
  • Ligand Density
    2 – 5 µeq/cm²  
  • Pore Size
    3 – 5 µm  
  • Reference Protein
    Lysozyme  
  • Typical Dynamic Binding Capacity 10% per unit
    0.48 mg/well  

Product Information

  • Brand
    Sartobind® S  
  • Membrane Adsorber Format
    96-Well Plates  
  • Membrane Type
    Strong cation exchanger  
  • Pack Size
    10  
  • Type
    Membrane adsorber (96-well plate)  
  • What you receive
    • 10 plates  
    • 1 operating instruction  
  • Vivawell Vac96 Vacuum Manifold

    The Vac96 vacuum manifold has been designed specifically for use with Sartobind® 96 multiwell plates. The long drip nozzles on the outlet eliminate cross-talk between flow channels.