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Full flexibility and outstanding crossflow filtration performance combined

SARTOFLOW® Advanced is a modular benchtop crossflow system that can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes. The system is optimized for ultrafiltration, microfiltration and diafiltration applications used in many downstream processes, such as purification of monoclonal antibodies, recombinant proteins or vaccines.


Availability (ex works):  On Request

The SARTOFLOW® Advanced system is suitable for flexible use in laboratory environments, for process development and clinical trials as well as for smallscale production batches. Several standardized options are available to enable you to obtain just the right system exactly tailored to meet your individual requirements. The system can also be upgraded with additional options if your requirements change during process development or production.

This Crossflow system is equipped with our proven DCU-4 control unit that readily communicates with BioPAT® MFCS software.

The SARTOFLOW® Advanced can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes. As a result, this gives you an exceptionally wide range of membrane surface areas. Since all Sartocon® crossflow cassettes have the same hydrodynamic flow path length, the SARTOFLOW® Advanced can be linearly scaled up from 0.1 to 2.1 m² of membrane area. Its unique compact design has an ultra-low loop volume of ~200 ml, making it possible to concentrate even small process batches.


SARTOFLOW® Systems — Crossflow Solutions for Lab and Process Development
en 436.4 kB


SARTOFLOW® Advanced — Full flexibility and outstanding crossflow filtration performance combi
en 398.9 kB


SARTOFLOW® Advanced — Full Flexibility and Outstanding Crossflow Filtration Performance Combined
en 666.4 kB


  • Dimensions (W×D×H)
    1,100 × 800 × 680 mm

Materials of Construction

  • Recirculation Vessel
    Stainless steel 316 L

Operating Conditions

  • Maximum Operating Pressure
    4 bar (58 psi)
  • Minimum Operating Volume
    ~200 mL

Power Requirements

  • Power Requirements
    230 VAC | 50 Hz 2.5 Amp; 120 VAC | 60 Hz 4 Amp

Product Information

  • Primary Product Type


  • Pump Output
    700 L/h @ 4 bar (60 psi)
  • Surface Roughness of Wetted Parts
    Ra <= 0.6 µm


  • Recirculation Vessel Volume
    1 L


  • Weight (approximate)
    135 kg
Hydrosart® Ultrafilter

Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for biological applications.

Hydrosart® Microfilter

Hydrosart® membranes are extremely hydrophilic, making it non-protein binding and virtually non-fouling. Hydrosart® mikrofiltration cassettes are available in 0.2 µm and 0.45 µm.

Polyethersulfone Microfilter

PESU cassettes are available in 0.1 µm pore size. Polyethersulfone membranes are designed for applications in the biotechnological and pharmaceutical industries. They can be used to remove the following cells from liquids:

  • Mammalian cells
  • Clostridia
  • Yeasts
  • Salmonella
  • Mycoplasma reduction

Polyethersulfone Ultrafilter

Polyethersulfone membranes (PESU) are stable polymer that feature a broad pH and temperature range. Polyethersulfone ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:

  • 1 kD
  • 5 kD
  • 8 kD
  • 10 kD
  • 30 kD
  • 50 kD
  • 100 kD
  • 300 kD