Full flexibility and outstanding crossflow filtration performance combined
SARTOFLOW® Advanced is a modular benchtop crossflow system that can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes. The system is optimized for ultrafiltration, microfiltration and diafiltration applications used in many downstream processes, such as purification of monoclonal antibodies, recombinant proteins or vaccines.
Item no.: SFADVANCED
Availability (ex works): On Request
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The SARTOFLOW® Advanced system is suitable for flexible use in laboratory environments, for process development and clinical trials as well as for smallscale production batches. Several standardized options are available to enable you to obtain just the right system exactly tailored to meet your individual requirements. The system can also be upgraded with additional options if your requirements change during process development or production.
This Crossflow system is equipped with our proven DCU-4 control unit that readily communicates with BioPAT® MFCS software.
The SARTOFLOW® Advanced can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes. As a result, this gives you an exceptionally wide range of membrane surface areas. Since all Sartocon® crossflow cassettes have the same hydrodynamic flow path length, the SARTOFLOW® Advanced can be linearly scaled up from 0.1 to 2.1 m² of membrane area. Its unique compact design has an ultra-low loop volume of ~200 ml, making it possible to concentrate even small process batches.
Dimensions (W×D×H)1,100 × 800 × 680 mm
Materials of Construction
Recirculation VesselStainless steel 316 L
Maximum Operating Pressure4 bar (58 psi)
Minimum Operating Volume~200 mL
Power Requirements230 VAC | 50 Hz 2.5 Amp; 120 VAC | 60 Hz 4 Amp
Primary Product TypeSystems
Pump Output700 L/h @ 4 bar (60 psi)
Surface Roughness of Wetted PartsRa <= 0.6 µm
Recirculation Vessel Volume1 L
Weight (approximate)135 kg
Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for biological applications.
Hydrosart® membranes are extremely hydrophilic, making it non-protein binding and virtually non-fouling. Hydrosart® mikrofiltration cassettes are available in 0.2 µm and 0.45 µm.
PESU cassettes are available in 0.1 µm pore size. Polyethersulfone membranes are designed for applications in the biotechnological and pharmaceutical industries. They can be used to remove the following cells from liquids:
- Mammalian cells
- Mycoplasma reduction
Polyethersulfone membranes (PESU) are stable polymer that feature a broad pH and temperature range. Polyethersulfone ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:
- 1 kD
- 5 kD
- 8 kD
- 10 kD
- 30 kD
- 50 kD
- 100 kD
- 300 kD