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SARTOFLOW® 20, 1.4435, F/R38, 4/P23, 7/ISO

The SARTOFLOW® 20 stainless steel holder with hydraulic is designed for crossflow applications from 200 l to 2500 l volumes. The holder is optimized for use with 4 Sartocon® up to 20 Sartocube® production scale crossflow cassettes (max. 14 m2). Typical applications of the SARTOFLOW® 20 system includes concentration and diafiltration of proteins, vaccines, antibodies, oligo nucleotides, endotoxin removal etc., cell harvesting and clarification processes.

Item no.:  179-2DI384237EM

Availability (ex works):  On Request


SARTOFLOW® 20 holder

The SARTOFLOW® 20 stainless steel holder is optimized for the use with up to twenty Sartocon® production scale Crossflow cassettes or four Sartocubes® (max. 14 m²).

It is designed for applications from 200 L to 2500 L volume.

Target use:

  • process development
  • preclinical trials
  • clinical trials
  • pilot lots
  • production

Sartocon® cassettes are available with Hydrosart ® or Polyethersulfone membrane types. The SARTOFLOW® 20 covers the whole range of pharmaceutical and biotechnological crossflow applications like concentration and diafiltration of proteins, vaccines, viruses, antibodies, oligo nucleotides, endotoxin removal etc. The system is also suitable for cell harvesting and clarification processes.

The Crossflow holder features the latest advances in crossflow design:

  • vertical orientation of cassettes
  • self draining systems
  • inline steamable
  • no welds
  • minimized hold up volume


Crossflow Filter Holders
en 790.3 kB


SARTOFLOW® 20 Stainless Steel Holder — Hydraulic Crossflow holder for Sartocon® cassettes
en 210.8 kB

Connections (Physical)

  • Connectors
    1" - 1½" Tri Clamp sanitary flange (DN25)


  • Dimensions (W×D×H)
    240 × 348 × 1230 mm
  • Feed / Retentate
    38.4 mm
  • Permeate
    23.7 mm

General Specifications

  • Cassette Capacity
    Sartocon® Cassettes: ≤ 20
  • Electro Polished
    Electro Polished
  • Mirror Inverted
  • Surface Roughness of Wetted Parts
    Ra <= 0.6 µm

Materials of Construction

  • Filter- and Clamping Plate Material
    316L (1.4435) stainless steel

Product Information

  • Type
    Stainless steel holder


  • Weight (approximate)
    70 kg
Hydrosart® Microfilter

Hydrosart® membranes are extremely hydrophilic, making it non-protein binding and virtually non-fouling. Hydrosart® mikrofiltration cassettes are available in 0.2 µm and 0.45 µm.

Hydrosart® Ultrafilter

Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for biological applications.

Polyethersulfone Microfilter

PESU cassettes are available in 0.1 µm pore size. Polyethersulfone membranes are designed for applications in the biotechnological and pharmaceutical industries. They can be used to remove the following cells from liquids:

  • Mammalian cells
  • Clostridia
  • Yeasts
  • Salmonella
  • Mycoplasma reduction

Polyethersulfone Ultrafilter

Polyethersulfone membranes (PESU) are stable polymer that feature a broad pH and temperature range. Polyethersulfone ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:

  • 1 kD
  • 5 kD
  • 8 kD
  • 10 kD
  • 30 kD
  • 50 kD
  • 100 kD
  • 300 kD