Sartocon® Slice ECO Hydrosart® Cassette
Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for biological applications.
Item no.: 3M51446801E--SW
Availability (ex works): On Request
Hydrosart® ECO ultrafiltration cassettes allows high mass transfer at low feed flow rates. The following nominal molecular weight cut offs are available:
- 10 kD
- 30 kD
- 100 kD
- 300 kD
Hydrosart® 100 kD main applications are:
- Virus purification
- Viral vectors like AAV
- Inactivated or attenuated viral vaccines: Polio, Dengue
- Virus like particles
- Removal of contaminants
- Large mAb constructs
BiosafetyAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Filtration Area0.14 m²
Materials of Construction
Integral FramePolypropylene (PP)
Sealing CompoundSilicone White (High chemical resistance)
Maximum Inlet Pressure4 bar
Bacterial Endotoxins< 0.18 EU/mL as determined by the LAL test
Flow Channel GeometryProtein conc. <20% /or viscosity max.3cp
Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Filter TypeCrossflow Filters
Primary Product TypeFilters
Cassette FormatSlice Cassettes
Ultrafilter100 kD Hydrosart® Ultrafilter Membrane
pH StabilitypH 2 – 14
Sartocon® Slice Holder filter holder is designed for low to medium volume applications from 200 ml to 100 L and optimized for the use with up to five Sartocon® Slice Crossflow cassettes (0.1 – 0.5 m²). The filterholder can be sterilized by autoclaving or inline steaming.