Sartocon® Slice 50 Hydrosart®
The Sartocon® Slice 50 is a ready to use 50 cm2 fully disposable crossflow module that is ideally suited for membrane screening and process development, available in a wide variety of MWCO’s and polymers. The Sartocon® Slice 50 can easily be used with the SARTOFLOW® Smart system as well as many other laboratory scale crossflow systems.
Item no.: 3D91447950ELLPU
Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for biological applications.
Hydrosart® E-Screen ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:
- 2 kD
- 5 kD
- 10 kD
- 30 kD
- 300 kD
Hydrosart® 300 kD main applications are:
- Virus concentration and purification
- Viral vectors: Lentivirus, Adenovirus, MVA, Vaccinia
- Inactivated or attenuated viral vaccines: Influenza, RSV
- Virus like particles, nanoparticles
- Contaminant removal: DNA, HCP
- Polysaccharide concentration
- Conjugate vaccines: removal of unconjugated polysaccharides
- Large protein concentration
BiosafetyAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Filtration Area50 cm²
Materials of Construction
Integral FramePolyvinylidene fluoride (PVDF)
Sealing CompoundNot Applicable
Maximum Inlet Pressure3 bar
Bacterial Endotoxins< 0.18 EU/mL as determined by the LAL test
Flow Channel GeometryProtein conc. >20% /or viscosity above.3cp
Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Filter TypeCrossflow Filters
Primary Product TypeFilters
Cassette FormatSlice 50 Cassettes
pH StabilitypH 2 – 14