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Sartocon® Hydrosart® Cassette

Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for biological applications.

Item no.:  3021443930E-BSW

Availability (ex works):  On Request

   

Hydrosart® E-Screen ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:

  • 2 kD
  • 5 kD
  • 10 kD
  • 30 kD
  • 100 kD
  • 300 kD

Hydrosart® 10 kD main applications are:

  • Removal of contaminants
  • Proteins
    • Albumin
    • Hemoglobin
  • ADC
  • Recombinant proteins
  • Antibody fragment bio-conjugates
  • Special mAb’s e.g. one heavy chain and 2 light chain mAb

Datasheet

Hydrosart® Ultrafiltration Cassettes — Protein purification, concentration and diafiltration
en 141.4 kB

User Manual

Manual Sartocube/Sartocon/ Slice/ Slice 200 E screen Silicone White
en 4.8 MB

Applications

  • Industry
    Pharma/Biotech

Compliance Information

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test
  • Biosafety
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filtration Area
    3 m²
  • Flow Channel Geometry
    Protein conc. >20% /or viscosity above.3cp

Materials of Construction

  • Integral Frame
    Polyvinylidene fluoride (PVDF)
  • Membrane Material
    Hydrosart®
  • Sealing Compound
    Silicone White (High chemical resistance)
  • Spacer
    Polypropylene (PP)

Operating Conditions

  • Maximum Inlet Pressure
    4 bar
  • pH Stability
    pH 2 – 14

Physicochemical Information

  • MWCO
    10 kD
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.

Product Information

  • Filter Type
    Crossflow Filters
  • Primary Product Type
    Filters

Specifications

  • Cassette Format
    Sartocube Cassettes
  • Filter Format
    Cassettes