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Sartocon® Slice Hydrosart® Cassette

Hydrosart® membranes are extremely hydrophilic, making it non-protein binding and virtually non-fouling. Hydrosart® mikrofiltration cassettes are available in 0.2 µm and 0.45 µm.

Item no.:  3051860701O--SG

Availability (ex works):  On Request

Hydrosart® is a stabilized cellulose derivative membrane polymer that has been optimized for the biotechnological and pharmaceutical industries. The Hydrosart® membrane is a stable polymer that features a broad pH and temperature range. Hydrosart is also extremely hydrophilic, making it non-proteinbinding and virtually non-fouling. As a result, it has extremely high flux. Hydrosart®’s wide temperature range makes it possible to sterilize the membrane by either steam or autoclaving. Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures. Hydrosart® membranes are designed for use in the biotechnological and pharmaceutical industries.

They can be used to remove the following from liquids:

  • Mammalian cells: CHO BHK
  • Bacteria: E. coli Pasteurella C. diphtheria
  • Yeasts
  • Cell Iysates Product

Hydrosart® has minimal adsorption of proteins, viruses, etc. Membrane retention is unaffected by repeated re-use. Hydrosart® has been validated to withstand in-line steam sterilization without any loss of integrity or changes in membrane retention.

Datasheet

Hydrosart® Open Channel Microfiltration Cassettes — Cell harvest and bacteria concentration
en 201.6 kB

Applications

  • Industry
    Pharma/Biotech

Compliance Information

  • Biosafety
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filtration Area
    0.1 m²

Materials of Construction

  • Integral Frame
    Polyvinylidene fluoride (PVDF)
  • Membrane Material
    Hydrosart®
  • Microfilter
    0.2 µm Hydrosart Microfilter Membrane Open Channel
  • Sealing Compound
    Silicone Grey
  • Spacer
    Polypropylene (PP)

Operating Conditions

  • Maximum Inlet Pressure
    4 bar

Physicochemical Information

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test
  • Flow Channel Geometry
    Microfilter Open Channel
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
  • Pore Size
    0.2 µm
  • Pore Size for Microfilter
    0.2 µm

Product Information

  • Filter Type
    Crossflow Filters
  • Primary Product Type
    Filters

Specifications

  • Cassette Format
    Slice Cassettes
  • Filter Class
    Microfilter
  • Filter Format
    Cassettes
  • pH Stability
    pH 2 – 14
Sartocon® Slice Holder
Sartocon® Slice Holder
Item no.:   17521---002

Sartocon® Slice Holder filter holder is designed for low to medium volume applications from 200 ml to 100 L and optimized for the use with up to five Sartocon® Slice Crossflow cassettes (0.1 – 0.5 m²). The filterholder can be sterilized by autoclaving or inline steaming.