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Virosart® CPV Capsule Height 4, Sanitary

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

Item no.:  5451328V4--FF--B

Availability (ex works):  On Request

   

Application:

  • Virus clearance: Virosart® CPV retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV).
  • Target molecule: The main applications for Virosart® CPV for virus filtration are monoclonal antibodies (mAb), antibody fragments (Fab) or small recombinant proteins (< 150 kD).
  • Positioning: Virosart® CPV is used towards the end of the purification process of biopharmaceutical products for the virus filtration. At this stage, the purity of the biopharmaceutical product is at its highest and so fouling of the filter by contaminants (DNA, CHOP, aggregates & lipoproteins) will be low.

Product Benefits:

  • Robust virus clearance: Virosart® CPV retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV). This filter offers highest virus safety over the entire flow decay profile independently of operating pressure.
  • Smart process transfer: Flexibility is given by using either cartridges in existing stainless steel housings or disposable capsules.
  • Ease of use: Virosart® CPV are tested for integrity using a water-based diffusion test, e.g. based on the Sartocheck® technology of Sartorius Stedim Biotech

Regulatory Compliance

  • Each individual filter is tested for integrity
  • Validated for ≥ 4 LRV removal of small non-enveloped viruses using bacteriophage PP7
  • Designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System
  • Meet or exceed the requirements for WFI quality standards set by the current USP
  • Non pyrogenic according to USP Bacterial Endotoxins
  • USP Plastic Class Test VI

Application Note

Impact of Pressure Release and Multiple Pressure Fluctuations on Virus Retention Performance of Virosart® CPV
en 1.1 MB
Effect of Flux Decay on Virus Retention
en 649.4 kB

Flyer

Virosart® Virus Filters - Reliable Retention Under All Circumstances
en 2.8 MB

User Manual

Directions for Use - Virosart® CPV Capsules
en 62.4 kB

 

  • Capsule/Cartridge Format
    Filter capsule
  • Connector Inlet
    ¾" Tri-Clamp 25 mm
  • Connector Outlet
    ¾" Tri-Clamp 25 mm
  • Delivery Condition
    Non sterile - Autoclavable
  • Filtration Area
    180 cm²
  • Integrity Tested
    Yes
  • Usage
    Easy to filter solutions

 

  • Filter Format
    Filter Capsules
  • Filter Type
    Virus Filters

 

  • Application
    • mAB Production
    • Recombinant Protein Production
Virosart® HC Capsule Height 4
Virosart® HC Capsule Height 4
Item no.: 5391328V4--FF--B

The high capacity virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in blood & plasma applications.

Sartocheck® 5 Plus Filter Tester
Sartocheck® 5 Plus Filter Tester
Item no.: 26787---FT---P

The Sartocheck® 5 Plus Filter Tester is an automatic filter integrity tester with automated Quality Risk Management (QRM) designed to cover the complete range of integrity testing from small syringe filters up to large multi-round housings and tangential flow cassettes.

Virosart® Max Capsule Height 4
Virosart® Max Capsule Height 4
Item no.: 54A1358N4--FF--B

Maximize your virus filter performance with adsorptive pre-filtration. Virosart® Max is a specifically optimized virus pre-filter significantly increasing downstream virus filter performance.