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Virosart® CPV

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

   

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Products (11)

Virosart® CPV Capsule Height 4, Hose barb
Brand
Virosart® CPV
Filtration Area
180 cm²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV Minisart - IT tested
Virosart® CPV Minisart - IT tested
Item no.: 545VM--------ITA
Brand
Virosart® CPV
Filtration Area
5 cm²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV 10" Standard Filter Cartridge
Brand
Virosart® CPV
Filtration Area
0.7 m²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV Minisart
Virosart® CPV Minisart
Item no.: 545VM----------B
Brand
Virosart® CPV
Filtration Area
5 cm²
Integrity Tested
No
Filter Type
Virus Filters
Virosart® CPV Midicap® Height 9
Virosart® CPV Midicap® Height 9
Item no.: 5455328V9--FF--V
Brand
Virosart® CPV
Filtration Area
0.2 m²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV 20" Standard Filter Cartridge
Brand
Virosart® CPV
Filtration Area
1.4 m²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV Capsule Height 4, Sanitary
Brand
Virosart® CPV
Filtration Area
180 cm²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV 20" Maxicaps®
Virosart® CPV 20" Maxicaps®
Item no.: 5457328V2--SS
Brand
Virosart® CPV
Filtration Area
1.4 m²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV 30" Maxicaps®
Virosart® CPV 30" Maxicaps®
Item no.: 5457328V3--SS
Brand
Virosart® CPV
Filtration Area
2.1 m²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV 10" Maxicaps®
Virosart® CPV 10" Maxicaps®
Item no.: 5457328V1--SS
Brand
Virosart® CPV
Filtration Area
0.7 m²
Integrity Tested
Yes
Filter Type
Virus Filters
Virosart® CPV 30" Standard Filter Cartridge
Brand
Virosart® CPV
Filtration Area
2.1 m²
Integrity Tested
Yes
Filter Type
Virus Filters
Results per page: | |

Application:

  • Virus clearance: Virosart® CPV retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV).
  • Target molecule: The main applications for Virosart® CPV for virus filtration are monoclonal antibodies (mAb), antibody fragments (Fab) or small recombinant proteins (< 150 kD).
  • Positioning: Virosart® CPV is used towards the end of the purification process of biopharmaceutical products for the virus filtration. At this stage, the purity of the biopharmaceutical product is at its highest and so fouling of the filter by contaminants (DNA, CHOP, aggregates & lipoproteins) will be low.

Product Benefits:

  • Robust virus clearance: Virosart® CPV retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV). This filter offers highest virus safety over the entire flow decay profile independently of operating pressure.
  • Smart process transfer: Flexibility is given by using either cartridges in existing stainless steel housings or disposable capsules.
  • Ease of use: Virosart® CPV are tested for integrity using a water-based diffusion test, e.g. based on the Sartocheck® technology of Sartorius Stedim Biotech

Regulatory Compliance

  • Each individual filter is tested for integrity
  • Validated for ≥ 4 LRV removal of small non-enveloped viruses using bacteriophage PP7
  • Designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System
  • Meet or exceed the requirements for WFI quality standards set by the current USP
  • Non pyrogenic according to USP Bacterial Endotoxins
  • USP Plastic Class Test VI

Application Note

Autoclaving Virosart® CPV Minisart® Devices
en 630.7 kB
I mpact of Pressure Release and Multiple Pressure Fluctuations on Virus Retention Performance of Virosart® CPV Virus Retentive Filters
en 865.3 kB
Effect of Flux Decay on Virus Retention
en 621.1 kB

Flyer

Virosart® Virus Filters - Reliable Retention Under All Circumstances
en 2.8 MB

User Manual

Directions for Use - Virosart® CPV Minisart®
en 332.4 kB
Directions for Use - Virosart® CPV Midicaps®
en 378.8 kB
Directions for Use - Virosart® CPV Capsules
en 62.4 kB
Directions for Use - Virosart® CPV Standard Filter Cartridges & Maxicaps®
en 264.1 kB

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