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HyperCel STAR AX, PRC Column 8 x 100, 5 mL Ion Exchange Chromatography Resin

HyperCel Star AX is a salt-tolerant anion exchanger with a primary amine as functional group. It can easily be integrated into a purification workflow without feed stream manipulation.

Item no.:  PRCSTARAX5ML

Availability:  On Request

   

HyperCel STAR AX is an industry-scalable anion exchange chromatography resin designed for high productivity protein capture at moderate or higher salt conductivity (2 to 15 mS/cm), typical of undiluted biological feedstocks (e.g. mammalian cell culture supernatants, E. coli feedstock, plasma, etc.).

 

Features and Benefits

- High dynamic binding capacity (DBC) at short residence time (2 minutes or lower)
- Direct capture of protein from undiluted feedstock at moderate or high conductivity
- Excellent flow rate properties for fast feedstock processing
- Distinctive selectivity, consistent in a broad conductivity range (2 – 15 mS/cm)
- Enhanced process economics
- Manufactured at large scale and to meet the demands of commercial users and regulatory authorities

 

Applications

- Direct capture of recombinant proteins, mono- and poly-clonal antibodies, plasma derivatives
- Direct Capture of Albumin from Undiluted Plasma
- Early Removal of CHOPs before Protein A Capture of a Monoclonal Antibody (MAb)

 

Available Formats for HyperCel STAR AX               

Pack SizeOrder Code
25 mL20197-026
100 mL20197-032
1 L20197-046
5 L20197-058
10 L20197-064

As pre-packed columns:

Pack SizeOrder Code
PRC Column 5x50 HyperCel STAR AX, 1 mLPRCSTARAX1ML
PRC Column 8x100 HyperCel STAR AX, 5 mLPRCSTARAX5ML
RoboColumn HyperCel STAR AX 200µL SR2STARAX
RoboColumn HyperCel STAR AX 600µLSR6STARAX

 

Datasheet

HyperCel™ STAR AX Ion Exchange Resin Salt Tolerant Advanced Recovery Anion Exchange Chromatography Resin
en 665.3 kB

 

  • Base Matrix
    Rigid cellulose beads
  • Bead Size
    60 - 90 µm
  • Operating Pressure
    < 3 barg (44psi)
  • Pack Volume
    5 mL
  • Resin Format
    Pre-packed column
  • Storage Conditions
    20% EtOH/1 M NaCl

 

  • Bed Height
    100 mm
  • Bed Volume
    5 mL
  • Flow Rate
    200-600cm/h
  • Ligand
    primary amine
  • Materials of Construction
    Polypropylene
  • Reference Protein
    BSA
  • Typical Dynamic Binding Capacity 10% per mL
    > 100 mg/mL BSA at pH 7.5 to 8.0 and conductivity to 15 mS/cm
  • What you receive
    1 column, instructions
  • pH Stability
    1 to 14 (short term), 2 to 12 (long term)

 

  • Application
    Resin screening and process optimization
  • Dimensions
    8 x 100 mm
  • Pack Size
    1 column per pack
  • Quality Standards
    CoA