CIMac™ AAV full/empty 0.1 mL Analytical Column (1.3 µm)

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CIMac™ AAV full/empty 0.1 mL Analytical Column (1.3 µm) CIMac™ AAV full/empty 0.1 mL Analytical Column (1.3 µm)
 

CIMac™ Analytical Columns combine all elaborate characteristics of CIM monoliths at analytical scale and are your perfect tool for analysis and control of manufacturing processes, ideal for process analytical technology (PAT). Designed for fast and reproducible HPLC monitoring and quantitation of proteins, viruses, pDNA, and other large biomolecules, they allow you to achieve rapid, high-resolution and flow-independent separations in a matter of minutes.

Item No.: 
110.8503-1.3
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

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The CIMac™ AAV full/empty 0.1 mL Analytical Columns are designed for fast and reproducible HPLC monitoring and quantitation of AAV samples. The high resolving capacity allows separation of empty viral capsids, aggregated and damaged particles from genome containing virus vectors. CIMac™ AAV full/empty-01 Analytical Column works with a full range of AAV serotypes and samples ranging from crude harvest all the way to final formulation, therefore doubling as an efficient PAT tool.

AAV full/empty features:

  • Strong anion exchanger
  • Enables fast and reproducible analysis and quantification in Adeno-associated virus (AAV)
  • Enables separation of empty and full virus capsids

Applications

  • Application
    Analytical Columns  

Connections (Physical)

  • Connectors
    10-32 UNF coned port, 0.0625" OD tubing connection  

Dimensions

  • Channel Size
    1.3 µm  
  • Diameter
    5.2 mm  
  • Length
    4.95 mm  

Features

  • Reusable
    Yes  

General Specifications

  • Flow Rate
    0.2 – 3 mL/min | 1 – 15 cm/min | 2 – 30 CV/min  

Materials of Construction

  • Materials of Construction
    Poly(glycidyl methacrylate -co- ethylene dimethacrylate)  

Operating Conditions

  • Maximum Operating Pressure
    15 MPa | 150 bar | 2175 psi  
  • Recommended Operating Temperature
    4 °C (39 °F) to 40 °C (104 °F)  
  • pH Stability
    Working range 2–13, cleaning in place 1–14  

Physicochemical Information

  • Bed Volume
    0.1 mL  
  • Ligand
    QA modified for AAV (strong anion exchanger, quaternary amine)  

Product Information

  • Brand
    CIMac™