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Ksep® 6000S System

Advanced, scalable, single-use automated centrifugation systems

Sartorius Ksep® systems provide robust, single-use bioprocessing solutions in the areas of recombinant therapeutics, cell therapy, vaccine manufacturing, and blood processing.

As per your process requirements, our fully-automated systems are optimized to recover supernatant or solids (cells | particles) in a continuous manner.

Ksep® systems solve the problems of traditional centrifugation and filtration based technologies by handling very high cell densities while providing high recoveries and product quality.

Item no.:  KSEP6000S

Availability:  On Request

   

Patented Ksep® systems technology is the only current technology that provides significant advantages for users that want to either harvest cells as product or discard cells as by-product during manufacturing.

Benefits

Smart Bioprocessing

  • Integrates and | or reduces processing steps and time
  • Improves recoveries of both solids and liquids
  • Provides option to selectively remove small particulate impurities, e.g. plastic generated, cell debris
  • Built-in scalability (4 – 6 fold) for development and manufacturing using the same system
  • Automated with option to run in complete manual mode
  • No hardware change for different applications
  • Handles low to high cell density cultures (>150 million cells/mL) equally well

Advanced Cell Handling

  • Imparts low shear on cells and keeps the cells intact
  • Maintains a healthy environment to sustain cell viability
  • Complete supernatant product recovery from slurry without dilution
  • Reduces intracellular protein contamination for harvest applications by keeping the cells intact

Ensures cGMP Manufacturing

  • Closed system with single-use class VI product contact surfaces
  • Simple, robust, and scalable
  • One software for all systems
  • Clog-free and continuous operation

Applications

  • Harvest | Clarification
  • Cell Therapy
  • Vaccine Manufacturing
  • Blood Processing
  • Learn more at www.sartorius.com/ksep-systems

Datasheet

kSep® Systems - Advanced, Scalable, Single-Use Automated Centrifugation Systems
en 531.5 kB

 

  • Cell Capacity per Cycle
    (CHO) Up to 1200 Billion
  • Connections
    ⅝″ × ⅜″ C-Flex
  • Connector Material
    C-Flex 374 (TPE)
  • Data Transfer
    • USB
    • J45-Ethernet
    • LAN
    • Twincat TS6100-OPC-UA server
    • OPC Expert
  • Flow Rate
    720 L/hr
  • Maximum Gravitational Force
    2,000 g
  • Power Requirements
    208 – 240 V3 Ph (US) | 400 V3 Ph (EU); 60 A
  • Volume
    6,000 mL (6 × 1,000 mL)
  • Working Volume
    10 – 2,000 L

 

  • Application
    • Cell Culture (Vaccine)
    • Cell Therapy
    • Cell Culture (recombinant proteins, mAbs)
Ksep® 6000S Harvest Clarification consumable kit  (Cell Clarification)

KSEP6000S-SET-HC consumable kit contains both the chamber set and the valve disposable set

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