Ambr® Crossflow

Study factors for manufacturability

Collect important information about the behaviour of the molecules in downstream processing already in an early stage

Automated, parallel trials

Up to 16 channels can be managed by one control station

Lowest process volumes

Small scale screening with 10 cm² membrane area | 5 mL recirculation volume

Flexibility of two different process scales

Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area

Choose your product

Products (7)

Ambr® Crossflow - 4 channel system including control station
Item no.
061-8A60
Including Control Station
Yes
Ambr® Crossflow - 16 channel system including control station
Item no.
061-8A63
Including Control Station
Yes
Ambr® Crossflow - 12 channel system (without control station)
Item no.
061-8A72
Including Control Station
No
Ambr® Crossflow - 8 channel system (without control station)
Item no.
061-8A71
Including Control Station
No
Ambr® Crossflow - 4 channel system (without control station)
Item no.
061-8A70
Including Control Station
No
Ambr® Crossflow - 12 channel system including control station
Item no.
061-8A62
Including Control Station
Yes
Ambr® Crossflow - 8 channel system including control station
Item no.
061-8A61
Including Control Station
Yes

Ambr® Crossflow provides at early development stages access to molecule behavior related to viscosity, buffer composition, shear stress and performance in the downstream process. It enables a lot of important additional decision criteria for the final candidate selection and speeds up this process significantly.

A small scale, high throughput automated system enables greater number of molecule | buffer combinations and process control conditions to be investigated. As a result early stage R&D productivity and efficiency will be improved significantly while costs per experiment are reduced. Ambr® Crossflow is a benchtop crossflow system optimised for ultrafiltration and diafiltration applications. It is a small scale screening system with a minimum recirculation volume of 5 mL and a dedicated new range of Ambr® CF Filter cassettes with 10 cm² membrane area.

The Ambr® CF Adapter Kit for Sartocon® Slice 50 accessory also enables the use of cassettes with 50 cm² membrane area.

Parallel operation is achieved with 4 independent crossflow channels per module, with up to 4 modules managed by one control station. This means Ambr® Crossflow is capable of performing membrane screenings with up to 16 Ambr® CF Filters simultaneously. Intuitive hardware and software design ensures that the system is quick to set up and easy to use, while full system automation ensures reliable process control and reduced manual intervention.

Learn more at www.sartorius.com/ambr-crossflow

Dimensions

  • Dimensions WxDxH
    620 × 600 × 540 mm (4 channel module)

General Specifications

  • Pump Output
    0 – 50 mL/min

Materials of Construction

  • Recirculation Vessel
    Polystyrene (PS)

Operating Conditions

  • Minimum Operating Volume
    5 mL

Product Information

  • Brand
    Ambr® crossflow
Ambr® CF Filter, Polyethersulfone 30 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter  Hydrosart®, 100 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter, Polyethersulfone 100 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

ambr® CF Filter  Hydrosart® 10 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® crossflow system.

Ambr® CF Filter, Polyethersulfone 5 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter  Hydrosart®, 5 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

Ambr® CF Filter  Hydrosart®, 30 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® crossflow system.

Ambr® CF Filter, Polyethersulfone 10 kD

The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.