Sartocon® Slice Hydrosart® Cassette
Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications.
- Hydrosart® is stable across a broad pH range.
- Hydrosart® is extremely hydrophilic, making it non-protein binding, and virtually non-fouling.
- Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations.
These features make Hydrosart® an ideal membrane for biological applications.
Item no.: 3051446801E--SW
Hydrosart® E-Screen ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:
- 2 kD
- 5 kD
- 10 kD
- 30 kD
- 100 kD
- 300 kD
Hydrosart® 100 kD main applications are:
- Virus purification
- Viral vectors like AAV
- Inactivated or attenuated viral vaccines: Polio, Dengue
- Virus like particles
- Removal of contaminants
- Large mAb constructs
IndustryPharma / Biotech
Bacterial Endotoxins< 0.18 EU/mL as determined by the LAL test
BiosafetyAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Filtration Area0.1 m²
Flow Channel GeometryProtein conc. >20% /or viscosity above.3cp
Cassette FormatSlice Cassettes
Materials of Construction
Integral FramePolyvinylidene fluoride (PVDF)
Sealing CompoundSilicone White (High chemical resistance)
Maximum Inlet Pressure4 bar
pH StabilitypH 2 – 14
Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
Filter TypeCrossflow Filters
Sartocon® Slice Holder filter holder is designed for low to medium volume applications from 200 ml to 100 L and optimized for the use with up to five Sartocon® Slice Crossflow cassettes (0.1 – 0.5 m2). The filterholder can be sterilized by autoclaving or inline steaming.
Full flexibility and outstanding crossflow filtration performance combined
SARTOFLOW® Advanced is a modular benchtop crossflow system that can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes. The system is optimized for ultrafiltration, microfiltration and diafiltration applications used in many downstream processes, such as purification of monoclonal antibodies, recombinant proteins or vaccines.