CIMmultus® is a unique and industry-proven line of pre-packed chromatographic monolithic columns featuring large flow-through channels, which make them ideal for purifying large biomolecules such as viruses (AAV, adenovirus, lentivirus, influenza, bacteriophages), nucleic acids (mRNA, pDNA), virus-like particles and exosomes.

Without the need for column packing, CIMmultus® columns are ready for use out of the box.

Available in:

  • Varied monolith volumes
  • Wide range of CIM® chemistries
  • Differing channel sizes

See more Products below

*Custom/bulk order quotes are provided within 72 hours of request.

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Products (14)

  • CIMmultus® QA 1 mL Monolithic Column (6 μm)
    Item no.
    311.5113-6
    Bed Volume
    1 mL
    Ligand
    QA (strong anion exchanger, quaternary amine)
    Channel Size
    6 µm
    Package Type
    Individually Packed
  • CIMmultus® C4 HLD 1 mL Monolithic Column (2 μm)
    Item no.
    311.8136-2
    Bed Volume
    1 mL
    Ligand
    C4 HLD (hydrophobic, butyl – high ligand density)
    Channel Size
    2 µm
    Package Type
    Individually Packed
  • CIMmultus® HiP2 Plasmid Process Pack® 1-1 mL
    Item no.
    100.0011-2
    Bed Volume
    1 mL
    Channel Size
    2 µm
    Package Type
    Integrated application solution
  • CIMmultus® PrimaS® 1 mL Monolithic Column (2 μm)
    Item no.
    311.5118-2
    Bed Volume
    1 mL
    Ligand
    Multimodal (anion exchange-hydrogen bonding)
    Channel Size
    2 µm
    Package Type
    Individually Packed
  • CIMmultus® Oligo dT18 (C6 Linker) 1 mL Monolithic Column (2 μm)
    Item no.
    311.1218-2
    Bed Volume
    1 mL
    Ligand
    Oligo dT18 coupled to CDI-activated matrix, C6 Linker
    Channel Size
    2 µm
    Package Type
    Individually Packed
  • CIMmultus® QA 1 mL Monolithic Column (2 μm)
    Item no.
    311.5113-2
    Bed Volume
    1 mL
    Ligand
    QA (strong anion exchanger, quaternary amine)
    Channel Size
    2 µm
    Package Type
    Individually Packed
  • CIMmultus® QA 1 mL Monolithic Column (1.3 μm)
    Item no.
    311.5113-1.3
    Bed Volume
    1 mL
    Ligand
    QA (strong anion exchanger, quaternary amine)
    Channel Size
    1.3 µm
    Package Type
    Individually Packed
  • CIMmultus® SO3 1 mL Monolithic Column (2 μm)
    Item no.
    311.6157-2
    Bed Volume
    1 mL
    Ligand
    SO3 (strong cation exchanger, sulfonate)
    Channel Size
    2 µm
    Package Type
    Individually Packed
  • CIMmultus® DEAE 1 mL Monolithic Column (2 μm)
    Item no.
    311.5114-2
    Bed Volume
    1 mL
    Ligand
    DEAE (weak anion exchanger, diethylamino)
    Channel Size
    2 μm
    Package Type
    Individually Packed
  • CIMmultus® Oligo dT18 (C12 Linker) 1 mL Monolithic Column (2 μm)
    Item no.
    311.1219-2
    Bed Volume
    1 mL
    Ligand
    Oligo dT18 coupled to CDI-activated matrix, C12 Linker
    Channel Size
    2 µm
    Package Type
    Individually Packed
  • CIMmultus® DEAE 1 mL Monolithic Column (1.3 μm)
    Item no.
    311.5114-1.3
    Bed Volume
    1 mL
    Ligand
    DEAE (weak anion exchanger, diethylamino)
    Channel Size
    1.3 μm
    Package Type
    Individually Packed
  • CIMmultus® SO3 1 mL Monolithic Column (6 μm)
    Item no.
    311.6157-6
    Bed Volume
    1 mL
    Ligand
    SO3 (strong cation exchanger, sulfonate)
    Channel Size
    6 µm
    Package Type
    Individually Packed
  • CIMmultus® C4 HLD 1 mL Monolithic Column (6 μm)
    Item no.
    311.8136-6
    Bed Volume
    1 mL
    Ligand
    C4 HLD (hydrophobic, butyl – high ligand density)
    Channel Size
    6 µm
    Package Type
    Individually Packed
  • CIMmultus® QA HR 1 mL Monolithic Column (2 μm)
    Item no.
    BIA-311.5213-2
    Bed Volume
    1 mL
    Ligand
    QA (strong anion exchanger, quaternary amine)
    Channel Size
    2 µm
    Package Type
    Individually Packed
  • CIMmultus® Monoliths are reusable chromatography devices for scalable high-resolution purification of complex biological samples. Inside the custom-designed housing is a single-piece stationary phase with homogeneous channel size and surface chemistry. This stationary phase is designed to simplify method transfer from development into production.

    Features

    • Available with a wide range of chemistries
    • Various channel size options
    • Scalable from 1 mL to 40 L
    • Single batch use or multiuse
    • cGMP compliant

    Benefits

    • Very fast processes by convective mass transport – resolution independent of flow
    • Ready to use columns
    • High-capacity for large molecules due to fully accessible void volume in the channels
    • Laminar flow minimizes shear stress resulting in high yields

    Product Information

    • Brand
      CIMmultus®