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Sartocon® Slice 200 Hydrosart® Cassette

Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications.

  • Hydrosart® is stable across a broad pH range.
  • Hydrosart® is extremely hydrophilic, making it non-protein binding, and virtually non-fouling.
  • Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations.

These features make Hydrosart® an ideal membrane for biological applications.

Item no.:  3081447902E--SW

Availability:  On Request

   

Hydrosart® E-Screen ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:

  • 2 kD
  • 5 kD
  • 10 kD
  • 30 kD
  • 100 kD
  • 300 kD

Hydrosart® 300 kD main applications are:

  • Virus concentration and purification
    • Viral vectors: Lentivirus, Adenovirus, MVA, Vaccinia
    • Inactivated or attenuated viral vaccines: Influenza, RSV
    • Virus like particles, nanoparticles
    • Contaminant removal: DNA, HCP
  • Polysaccharide concentration
    • Conjugate vaccines: removal of unconjugated polysaccharides
  • Large protein concentration

Datasheet

Sartocon® Slice 200 - Low hold-up volume Crossflow cassette format for low volume applications
en 124.8 kB

User Manual

Directions for Use - Sartocube® | Sartocon® | Sartocon® Slice | Sartocon® Slice 200 Cassettes
en 1.1 MB

Dimensions

  • Filtration Area
    0.02 m²
  • Flow Channel Geometry
    Protein conc. >20% /or viscosity above.3cp

General Specifications

  • Cassette Format
    Slice 200 Cassettes
  • Filter Format
    Cassettes

Operating Conditions

  • Maximum Inlet Pressure
    4 bar
  • pH Stability
    pH 2 – 14

eShop Dynamic Attributes

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test
  • Biosafety
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
  • Filter Type
    Crossflow Filters
  • Industry
    Pharma / Biotech
  • Integral Frame
    Polyvinylidene fluoride (PVDF)
  • MWCO
    300 kD
  • Membrane Material
    Hydrosart®
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
  • Sealing Compound
    Silicone White (High chemical resistance)
  • Spacer
    Polypropylene (PP)
Sartocon® Slice Holder
Sartocon® Slice Holder
Item no.: 17521---002

Sartocon® Slice Holder filter holder is designed for low to medium volume applications from 200 ml to 100 L and optimized for the use with up to five Sartocon® Slice Crossflow cassettes (0.1 – 0.5 m²). The filterholder can be sterilized by autoclaving or inline steaming.

SARTOFLOW® Advanced
SARTOFLOW® Advanced
Item no.: SFADVANCED

SARTOFLOW® Advanced
Full flexibility and outstanding crossflow filtration performance combined

SARTOFLOW® Advanced is a modular benchtop crossflow system that can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes. The system is optimized for ultrafiltration, microfiltration and diafiltration applications used in many downstream processes, such as purification of monoclonal antibodies, recombinant proteins or vaccines.

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