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Vivaspin® 500 Centrifugal Concentrators

500 µl - 5 µl
One step procedure for small sample amounts.


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Vivaspin® centrifugal concentrators are disposable ultrafiltration devices for the concentration of biological samples. Vivaspin® 500 centrifugal filter units offer a simple, one step procedure for sample concentration with starting volumes up to 500 µl. They can effectively be used in fixed angle rotors accepting 2.2 ml centrifuge tubes. The patented vertical membrane design and thin channel filtration chamber (US 5,647,990), minimises membrane fouling and provides high speed concentrations. Vivaspin® 500 units are available with PES membrane in a wide range of molecular weight cut-offs. Concentrate recoveries of > 90% can be reached in less than 30 min. The dead stop pocket prevents concentration to dryness.

  • High flux PES membrane
  • High retentate recovery > 90 %
  • Vertical membrane design for ultra fast concentration
  • Universal rotor compatibility
  • Safe sample concentration due to dead-stop volume
  • Convenient concentrate recovery by pipetting
  • Volume graduation for easy reading/monitoring

Vivaspin® 500 Polyethersulfone, 10 kDa

Performance Characteristics

Time to concentrate up to 30x [min.] at 20°C Concentrate recovery %
Start volume 500 μl 500 μl
Aprotinin 0.25 mg/ml (6,500 MW)
3,000 MWCO PES 30 96 %
BSA 1.0 mg/ml (66,000 MW)
5,000 MWCO PES 15 96 %
10,000 MWCO PES 5 96 %
30,000 MWCO PES 5 95 %
IgG 0.25 mg/ml (160,000 MW)
30,000 MWCO PES 10 96 %
50,000 MWCO PES 10 96 %
100,000 MWCO PES 10 96 %

Application Note

Sartorius Ultrafiltration Products for the Concentration and Purification of Viruses – a Short Review
en 192.9 kB
Sartorius Ultrafiltration Products in the Preparation of Biological and Medical Nanocarriers – a Short Review
en 944.4 kB
Concentration to a Defined Final Volume with Vivaspin® Turbo 15 PES, Vivaspin® Turbo 4 PES and Vivaspin® 500 PES
en 482.7 kB
Treatment of Vivaspin® concentrators for improved recovery of low-concentrated protein samples
en 485.8 kB
Urine Protein Concentration with Vivaspin® Concentrators
en 540.6 kB
Desalting and Buffer Exchange with Vivaspin® Centrifugal Concentrators
en 735.9 kB
Using Ultrafiltration with Vivaspin® 500 as an Alternative to Sample Volume Reduction by Lyophilization
en 127.6 kB


Ultrafiltration Family
en 1.6 MB

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