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MSCgo™ Chondrogenic Differentiation Supplement Mix

A supplement mix for MSCgo Chondrogenic Differentiation Medium, a complete, serum-free, xeno-free media, optimized for directed differentiation of hMSCs to chondrocytes

Item no.:  05-221-1D

Price:  $54.30

1 Piece
 

MSCgo Chondrogenic Differentiation Medium is a serum-free (SF) and xeno-free (XF) formulation developed for optimal differentiation of human mesenchymal stem cells (hMSC) to mature chondrocytes. The MSCgo Chondrogenic Differentiation Medium is validated to efficiently differeniate hMSC from a variety of sources, including bone marrow (BM-MSC), adipose tissue (AT-MSC), and umbilical cord tissue (UC-MSC).

The MSCgo Chondrogenic Differentiation Medium kit includes a basal medium and supplement, containing all growth factors and supplements necessary for a complete chondrogenic differentiation medium.  No additional supplements are required.

The MSCgo Chondrogenic Differentiation protocol is part of a complete system for multipotency evaluation of hMSCs.  This kit enables reliable differentiation of hMSCs to mature chondrocytes without background differentiation or interruption in cellular metabolism.

Features

  • Serum-free, xeno-free medium
  • All required growth factors and supplements included in kit
  • Reliable differentiation to mature chondrocytes
  • Each lot is application tested
  • Does not contain antibiotics

Components

  • MSCgo Chondrogenic Differentiation Basal Medium:  100 mL
  • MSCgo Chondrogenic Differentiation Supplement Mix :  10 mL

Chondrogenesis Results

Chondrogenic differentiation of hMSC in 3D spheroid culture in the formation of cartilage with a typical extracellular matrix rich of Aggrecan. Aggrecan is a proteoglycan that can be used as an indicator for cartilage formation and can be detected with Alcian Blue, a dark-blue copper-containing dye that acts as an indication of mature chondrocytes. The staining intensity can be vary using different hMSC (e.g. source, age, and passage number). 

Datasheet

MSCgo™ Differentiation Media - Advanced Adipogenesis, Osteogenesis, and Chondrogenesis From hMSCs
en 539.5 kB

Poster

A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources
en 1.2 MB

Publication

MSCgo™ Differentiation Media Selected References
en 109.7 kB

Safety Datasheet

MSCgo™ Chondrogenic Differentiation Supplement Mix MSDS (GB)
en 129.1 kB
MSCgo™ Chondrogenic Differentiation Supplement Mix MSDS (US)
en 151.7 kB

User Manual

MSCgo™ Chondrogenic XF Instructions For Use
en 308.9 kB

Applications

  • Application Area
    Chondrogenic Differentiation

Features

  • Serum Free
    Yes

Physicochemical Information

  • Adherence/Suspension
    Suspension

Sterility

  • Delivery Condition
    Sterile

Volumes

  • Volume
    10 ML

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