Vitronectin is a secreted glycoprotein that can support cell adhesion through binding to various integrins and proteoglycans. Recombinant vitronectin ACF can function as a chemically-defined matrix component for the attachment of human embryonic and induced pluripotent stem cells in a feeder-free culture system. Recombinant Vitronectin ACF is a 459 amino acid, single-chain, monomeric protein, which migrates at an apparent molecular weight of 75 kDa by SDS-PAGE under reducing conditions. The calculated molecular weight of Vitronectin ACF is 52.2 kDa.
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Application AreaCell attachment