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Virosart® CPV

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

Virosart® CPV 10" Standard Filter Crtdg

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

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Virosart® CPV MidiCap height 9
Virosart® CPV MidiCap height 9
Order Number: 5455328V9--FF--V

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

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Virosart® CPV 20" MaxiCaps® - New Design
Virosart® CPV 20" MaxiCaps® - New Design
Order Number: 5457328V2--SS

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

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Virosart® CPV Capsule height 4
Virosart® CPV Capsule height 4
Order Number: 5451328V4--FF--B

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

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Virosart® CPV Minisart IT tested
Virosart® CPV Minisart IT tested
Order Number: 545VM--------ITA

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

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Application:

  • Virus clearance: Virosart® CPV retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV).
  • Target molecule: The main applications for Virosart® CPV for virus filtration are monoclonal antibodies (mAb), antibody fragments (Fab) or small recombinant proteins (< 150 kD).
  • Positioning: Virosart® CPV is used towards the end of the purification process of biopharmaceutical products for the virus filtration. At this stage, the purity of the biopharmaceutical product is at its highest and so fouling of the filter by contaminants (DNA, CHOP, aggregates & lipoproteins) will be low.

Product Benefits:

  • Robust virus clearance: Virosart® CPV retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV). This filter offers highest virus safety over the entire flow decay profile independently of operating pressure.
  • Smart process transfer: Flexibility is given by using either cartridges in existing stainless steel housings or disposable capsules.
  • Ease of use: Virosart® CPV are tested for integrity using a water-based diffusion test, e.g. based on the Sartocheck® technology of Sartorius Stedim Biotech

Regulatory Compliance

  • Each individual filter is tested for integrity
  • Validated for ≥ 4 LRV removal of small non-enveloped viruses using bacteriophage PP7
  • Designed, developed and manufactured in accordance with an ISO 9001 certified Quality Management System
  • Meet or exceed the requirements for WFI quality standards set by the current USP
  • Non pyrogenic according to USP Bacterial Endotoxins
  • USP Plastic Class Test VI

Application Note

Appl_Autoclaving-Virosart-Minisart-devices_SPK4110-e.pdf
en 870.3 kB
Appl_Virosart_CPV_SPK4111-e.pdf
en 1.1 MB
Appl_Virosart-01_SPK4109-e.pdf
en 649.4 kB

Datasheet

Data_Virosart_CPV_Capsule_Family_SPK2178-e.pdf
en 1.3 MB

Flyer

Virosart® — Highest virus safety for your patient — Next generation virus clearance concepts
en 886.6 kB

User Manual

Virosart® CPV Capsules
en 56.8 kB
Virosart® CPV MidiCaps®
en 110.0 kB
Virosart® CPV Minisart®
en 189.1 kB