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Sartobind® Cassettes

As membrane chromatography processes grow in size, multiple Sartobind® cassettes of 0.8 or 1.6 L volume can now be used to accommodate the needed process scale. Three different stainless steel holders are available for maximum membrane volumes of up to 20, 50, or 100 L. The fluid path within the cassettes is the same as for Sartobind® capsules, so process development and small scale data can be extrapolated to the new format. Scaling up has never been easier!

Sartobind® Q 1.6 L, 8 mm, 1 cassette, γ

Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity.

The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

Virus purification processes that cannot be sterile filtered prior to filling due to virus size and continuous manufacturing could especially benefit from the sterile gamma irradiated version.

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Sartobind® Q 0.8 L, 4 mm, 1 cassette, γ

Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity.

The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

Virus purification processes that cannot be sterile filtered prior to filling due to virus size and continuous manufacturing could especially benefit from the sterile gamma irradiated version.

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Sartobind Phenyl Cassette 1.6 L, 8 mm bed height

Sartobind® Phenyl accomplishes polishing and capturing ten times faster than do conventional HIC resins. The membrane shows comparable, high binding capacity, without size exclusion effects, for proteins in a range of 20 mg mAb/mL membrane, as well as excellent resolution and impurity reduction.

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Sartobind® Q Cassette 1.6 L, 8 mm bed height

Sartobind® Q strong ion exchangers are perfect tools for the polishing of monoclonal antibodies for the removal of viruses, DNA, host cell proteins, leached Protein A, and endotoxins. As size exclusion effects are neglectible, they are suited for purification of viruses such as adeno or lentiviruses displaying one order of magnitude higher dynamic binding capacity.

The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

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Sartobind® S Cassette 0.8 L, 4 mm bed height

Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.

The cassette design eliminates the 5 L size limitation for membrane adsorbers and offers simple pod-like modular system up to 100 L membrane volume.

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