Skip to content Skip to navigation menu

Virosart® HC 20" Standard Filter Cartridge

The high capacity virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in blood & plasma applications.

Item no.:  5392528V2

Availability (ex works):  On Request

Application:

  • Virus clearance: Virosart® HC retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV).
  • Target molecule: The main applications for Virosart® HC for virus filtration are hydrophobic feed streams such as IVIG or any other plasma derivates as well as hydrophobic antibodies & recombinant proteins (< 150 kD).
  • Positioning: Virosart® HC is used towards the end of the purification process of biopharmaceutical products for the virus filtration. At this stage, the purity of the biopharmaceutical product is at its highest and so fouling of the filter by contaminants (DNA, CHOP, aggregates & lipoproteins) will be low.

Product Benefits:

  • Robust virus clearance: Virosart® HC retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV). This filter offers highest virus safety over the entire flow decay profile independently of operating pressure.
  • Smart process transfer: Flexibility is give by using either cartridges in existing stainless steel housings or disposable capsules.
  • Ease of use: Virosart® HC are tested for integrity using a water-based diffusion test, e.g. based on the Sartocheck® technology of Sartorius Stedim Biotech

Regulatory Compliance:

  • Each individual filter is tested for integrity
  • Validated for ≥ 4 LRV removal of small non-enveloped viruses using bacteriophage PP7
  • Designed, developed and manufactured in accordance with an
  • ISO 9001 certified Quality Management System
  • Meet or exceed the requirements for WFI quality standards set by the current USP
  • Non pyrogenic according to USP Bacterial Endotoxins
  • USP Plastic Class Test VI

Datasheet

Data_Virosart_HC_Capsule_Family_SPK2179-e.pdf
en 1.5 MB

Flyer

Virosart® — Highest virus safety for your patient — Next generation virus clearance concepts
en 886.6 kB

Poster

Adsorptive Pre-filtration to Increase Virus Filter Performance and Overall Process Robustness in Blood Derived Processes
en 1.6 MB
Poster_Virus_Retentive_Filtration_A1-e.pdf
en 290.7 kB

User Manual

Virosart® HC 539… Standard Filter Cartridges & T-Style MaxiCaps®
en 515.1 kB

Applications

  • Application
    Blood and Plasma
  • Industry
    Pharma/Biotech

Connections (Physical)

  • Connector Inlet
    2-Flange Bayonet Adapter with 226 Double O-ring (25)
  • Connector Outlet
    N/A

Dimensions

  • Filtration Area
    1.8 m²
  • Height
    572 mm

Features

  • Integrity Tested
    Yes

Product Information

  • Filter Type
    Virus Filters
  • Primary Product Type
    Filters

Specifications

  • Filter Format
    Cartridges
Virosart® CPV 20" Standard Filter Crtdg
Virosart® CPV 20" Standard Filter Crtdg

The PES based virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in biopharmaceutical applications. Virosart® CPV is the optimal virus filter for monoclonal antibodies or small recombinant proteins.

Item no.:   5452528V2
Sartocheck® 4 Plus Filter Tester v 3.2
Sartocheck® 4 Plus Filter Tester v 3.2

Fully automatic filter integrity testing device. In full compliance with 21 CFR Part 11 and GAMP5. A large accessory package makes Sartocheck 4 plus flexible, powerful and creates safe solutions for almost all customer needs.

Item no.:   26288---FT
Virosart® Max 20" Standard Filter Cartridge
Virosart® Max 20" Standard Filter Cartridge

Maximize your virus filter performance with adsorptive pre-filtration. Virosart® Max is a specifically optimized virus pre-filter significantly increasing downstream virus filter performance.

Item no.:   54A2558N2
Single round Housing T-Type
Single round Housing T-Type

Sartorius Stedim Biotech Sanitary Single Round Filter Housings are specifically designed for liquid filtration applications of the Bio-Pharmaceutical Industry. Application: bioreactors, CIP skids, autoclaves, lyophilizers and process tanks.

Item no.:   7S12LEN00147