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BioSealer® is a fully automated device used for sterile disconnection, designed to produce permanent and consistent leak free seals on thermoplastic tubing.

Item no.:  16363-P9

Availability:  On Request

The BioSealer® is a fully automated device,designed to produce permanent and consistent leak free seals on thermoplastic tubing. Operating Principle: The inserted empty or liquid filled tube gets compressed and heated between two ceramic heating elements. The liquid is evacuated from the internal tube section and the heat and the compression force fuse the tube to a homogeneous section. This section can be cut in the middle by the use of sharp scissors.

  • Flexibility: The unit is sealing from 1/4” OD tubing up to 3/4” OD tubing
  • Easy to use: The BioSealer® is optionally available with a removable sealing head. The sealing head can be used 3 m away form the actual device. This ensures an easy adaptation to various space requirements.
  • Short sealing cycles: Depending on the tubing size and quality, the average sealing cycle times are between 1 to 4 minutes


BioSealer® — For permanent and consistent leak free seals
en 155.9 kB

Product properties

  • Condition of Use
  • Technology
  • Primary Product Type
    Sealer and Welders
  • Type of Disconnection
    Thermal disconnection
  • Sealing Head Type
  • Temperature range
    20 – 30 °C

Technical attributes

  • Area of Application
    Connecting & Disconnecting
  • Process Step
    • Drug Substance Purification
    • Drug Product Formulation
    • Media
    • Buffer
    • Cell Harvest & Downstream Processing Intermediates
  • Tube Type
  • Tube Size (ID – OD)
    ¼ in. – ¾ in. OD
  • Power Requirements
    100-240 V/ 47 - 63 Hz
  • Housing Material
    Stainless steel
  • Relative Humidity
    35% – 65%
  • IP Rating
    IP 20
  • Compression Head
    Aluminum anodised
  • Maximum Tube OD
    ¾ in.
  • Minimum Tube OD
    ¼ in.
  • Sealing Cycle
    1 – 4 minutes depending on tube size and quality
  • Dimensions (WxDxH)
    220 × 150 × 210 mm
  • Weight (approx.)
    3 kg
  • Material Tubings
    C-Flex® 082
  • Meter Dimensions
    ⅜ in. × 5/8 in. only
  • Thickness Requirement for Wall
    ¼ in.
  • Wall Thickness
    3.2 mm