Ksep® Systems

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Ksep® Systems Ksep® Systems Ksep® Systems
 

Advanced, scalable, single-use automated centrifugation systems

Sartorius Ksep® systems provide robust, single-use bioprocessing solutions in the areas of recombinant therapeutics, cell therapy, vaccine manufacturing, and blood processing.

As per your process requirements, our fully-automated systems are optimized to recover supernatant or solids (cells | particles) in a continuous manner.

Ksep® systems solve the problems of traditional centrifugation and filtration based technologies by handling very high cell densities while providing high recoveries and product quality.

See more Products below

*Custom/bulk order quotes are provided within 72 hours of request.

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Products (3)

  • Ksep® 6000S System
    Ksep® 6000S System
    Item no.
    KSEP6000S
    Cell Capacity per Cycle
    (CHO) Up to 1200 Billion
    Working Volume
    100 – 2,000 L
    Volume
    6,000 mL (6 × 1,000 mL)
  • Ksep® 400 System
    Ksep® 400 System
    Item no.
    KSEP400
    Cell Capacity per Cycle
    (CHO) Up to 80 Billion
    Working Volume
    10 - 200 L
    Volume
    400 mL (4 × 100 mL)
  • Ksep®50 single-use Centrifuge System
    Ksep®50 single-use Centrifuge System
    Item no.
    KSEP50
    Cell Capacity per Cycle
    (CHO) Up to 10 Billion
    Working Volume
    0.1 - 20 L
    Volume
    50 mL (2 x 25 mL)

    • Patented Ksep® systems technology is the only current technology that provides significant advantages for users that want to either harvest cells as product or discard cells as by-product during manufacturing.

    Benefits

    Smart Bioprocessing

    • Integrates and | or reduces processing steps and time
    • Improves recoveries of both solids and liquids
    • Provides option to selectively remove small particulate impurities, e.g. plastic generated, cell debris
    • Built-in scalability (4 – 6 fold) for development and manufacturing using the same system
    • Automated with option to run in complete manual mode
    • No hardware change for different applications
    • Handles low to high cell density cultures (>150 million cells/mL) equally well

    Advanced Cell Handling

    • Imparts low shear on cells and keeps the cells intact
    • Maintains a healthy environment to sustain cell viability
    • Complete supernatant product recovery from slurry without dilution
    • Reduces intracellular protein contamination for harvest applications by keeping the cells intact

    Ensures cGMP Manufacturing

    • Closed system with single-use class VI product contact surfaces
    • Simple, robust, and scalable
    • One software for all systems
    • Clog-free and continuous operation

    Applications

    • Harvest | Clarification
    • Cell Therapy
    • Vaccine Manufacturing
    • Blood Processing
    • Learn more at www.sartorius.com/ksep-systems

    Applications

    • Application
      • Cell Culture (Vaccine)  
      • Cell Therapy  
      • Cell Culture (recombinant proteins, mAbs)  

    Product Information

    • Brand
      Ksep®  
  • Ksep® Consumable Kits
    Ksep® Consumable Kits
    Item no.
    M_kSep_consumable-kit

    Concentration-Wash-Harvest and Harvest Clarification Consumable Kits for cell harvest and cell clarification with Ksep®50, Ksep®400 or Ksep®6000S centrifugation system.