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Freeze and Thaw Systems
The freeze & thaw systems consist of bags and containers for freeze and thaw processes of biopharmaceuticals in manufacturing and process development or in commercially available equipment such as laboratory freezers, walk-in freezers, cold rooms or temperature controlled cabinets.
Celsius® FFT is a ready-to-use container, composed of a bag and a protective shell, designed for freezing and thawing biopharmaceutical solutions in commercially available equipment such as laboratory freezer, walk-in freezer, cold room or temperature controlled cabinet. It is available in 2, 4 , 6 and 12 l. Celsius® FFT combines the unique design of a flexible freeze and thaw bag with an integral protective shell. The robustness of this assembly ensures protection, support and easy handling.
Celsius® S3 is a tool to execute freeze-thaw process development and stability studies using a minimal amount of product. The Celsius® S3 freeze and thaw system is composed of a temperature controlled unit (CryoPilot A), a module for bag insertion (S3 Module), a mixing plattform for the thawing steps (CryoMixer Jr), a computer with data acquisition system and a custom-built software (CryoPilot Software) as well as single-use bags (Celsius®-Pak 30 ml and 100 ml).
Celsius®-Pak provides uniform and reproducible freeze and thaw processes for biopharmaceuticals in manufacturing and process development. They are available in a range of volumes from 30 ml to 16.6 l. Celsius®-Paks are specifically designed for controlled freezing, thawing and long term frozen storage of biopharmaceuticals such as process intermediates, bulk drug substances, products in clinical phases (pre, I, II ) or vaccines.