Always the Best Solution for Your Harvest
Sartoclear® Depth Filters
Sartoclear® filters are cellulose-based depth filters developed for demanding clarification applications in the biotechnological and pharmaceutical industries. The wide range of grades offers a solution for a variety of applications such as post centrifuge filtrations, perfusion processes, and direct harvests with moderate cell densities.
- Mammalian cell culture harvests
- Microbial lysates
- Removal of precipitates from sera and plasma
- Particle and colloid removal from process intermediates
- Media Filtration
Maximize Product Recovery
- Manifold set comes with pre-installed tubing on vents and drains
- Tubing with quick connectors at the end can be hooked up with pressurized air or bags
- Retained medium is recovered through controlled air pressure
Overview and Ordering Information
Sartoclear® filters are available in various device formats serving you from the first steps, throughout clinical phases and up to large scale manufacturing while always keeping the same filter material.
Sartoclear® Caps are easy to use screening devices that help you to find the best grade for your application.
Sartoclear® Depth Filter
Sartoclear® Depth Filter Cassettes are single-use filtration devices especially designed for biopharmaceutical clarification applications. The modular devices provide linear scalability from small to large scale processes. Three different sizes allow for a seamless adaptation to different process fluid volumes.
Find the Optimal Grade for Your Application
Sartoclear® DL-Series are high capacity depth filters made of two distinct filtration layers. The primary coarser layer is followed by a second finer layer which enables the removal of a broader spectrum of particles in a single step.
The Sartoclear® DL-Series are pre-selected and optimized to serve the most common biopharmaceutical applications.
Sartoclear® S-Series are single layer depth filter media grades for more specific applications such as vaccines and process intermediates with a lower or homogenous particle load.
The Sartoclear® S-Series are also available as filter sheets for plate and frame filtration systems which are often used in the plasma industries.
Grade Description of Sartoclear® DL-Series
|DL90||SX00||S200||Very coarse primary grade on top of a coarse secondary filter for filtrations with high solid concentrations||Primary clarification of mammalian cell cultures, insect cell cultures, microbial fermentations, vaccines|
|DL75||S600||S200||Pure cellulose pre-filter combined with a coarse secondary filter||Primary clarification of mammalian cell cultures, insect cell cultures, microbial fermentations, vaccines|
|DL60||S400||S080||Coarse primary grade with a secondary fine filtration grade for lower to moderate solid concentrations||Post-perfusion bioreactors, vaccines|
|DL20||S080||S040||Fine filtration grade combined with a standard bioburden reduction grade for the removal of particles||Post centrifuge mammalian cell cultures, post primary depth filtration, process precipitates|
|DL10||S080||S010||Fine filtration grade followed by very tight secondary filter for the removal of high concentrations of small particles||Post centrifuge microbial (e.g. E. coli ) lysates, post primary depth filtration step, process precipitates|
1 The listed examples are indicative and need to be confirmed by small scale tests
System Overview Sartoclear® Depth Filter
An optional pressure safety device is available to avoid excess pressure during compressed air draining of the filters.