Weigh the Smallest Quantities Directly into Heavy Containers

Cubis® high-capacity micro balances for preparation of calibration standards in the pharmaceutical laboratory

The new high-capacity micro balances provide the world’s highest resolution of more than 60 million divisions in micro weighing instruments manufactured in large series.

The most recently expanded Cubis® portfolio now features four high-end balances: Two full-resolution balances with a weighing capacity of 31 g and 61 g, respectively, and a readability of 1 µg, as well as two PolyRange models with weighing capacity range levels of 6 g |31 g and 12 g | 61 g and readability levels of 1 µg | 10 µg.

An additional model, MSA116P, even lets you use container sizes with volumes of up to 250 mL, such as long-necked flasks or HPLC bottles, to directly use these to weigh minimum quantities of only 1.64 mg.

This will ease your work in preparing calibration standards as you will no longer have to resort to weighing a minimum sample amount on a “normal” micro balance or experience the risk of sample loss when transferring it to a larger vessel.

Forget Inconvenient and Error-Prone Sample Transfer

Have you been weighing your expensive samples in the smallest vessels or on weigh boats or paper in your lab, and then needing to transfer these amounts to larger containers in the next step? Now you can forget about risking inaccuracy and wasting costly material. The new Sartorius high-capacity micro balances offer you an excellent, work-saving solution. They provide a choice of weighing capacities of up to 61 g with a readability of 1 µg and of a capacity of 111 g and a fine range of 12 g with a readability of 2 µg.

No more quantitative transfer is needed, as you can weigh your sample directly into a large, heavy flask appropriate for preparing your reference standards. Moreover, the balances feature an optimal minimum weight capability in compliance with USP Chapter 41. This means you can weigh the smallest quantities, maximizing the use of your costly samples, which may be available only in small amounts.

  • Save on purchasing expensive sample quantities as the balance’s optimal USP minimum weight capability reduces the amounts required.
  • Reduce costs by eliminating the need for using weigh boats or paper.
  • Save an extra step and prevent errors in your results due to sample loss during quantitative transfer.
  • Stop worrying about whether you have sufficient weighing capacities, fine ranges and readabilitie

Just think in terms of the volumetric container sizes and minimum weights.

Always the Right Flask Position for Optimal Manual Dosing

A sample holder just right for every lab container enables you to work accurately and safely. That is why Sartorius has designed an adjustable sample holder YSH02 with “one-size-fits-all” flexibility. It lets you optimally position the flask you use for preparing stock solutions or reference standards so you can conveniently dose even the smallest quantities of a substance accurately.

Whether you use long-necked round-bottom flasks, cylindrical HPLC bottles or test tubes, you can adjust the Sartorius titanium sample holder to the size of your vessel. Easily adjust the angle and position for ergonomic and reliable dosing. The extended space on our large 50 mm diameter weighing pan is ideal for vessels requiring a larger support area to prevent them from tipping over (comes as standard with weighing modules 66S, 66P and 116P).

The Complete Weighing Process under Control – for Optimal Weighing Performance

The larger the container you use, the more it is exposed to environmental influences:
Temperature, buoyancy, air currents, electrostatic effects, etc., all have a considerable impact on the response time and the stability of weight readouts. The following principle also applies in this case: The smaller the sample quantities used, the larger the relative measuring errors become. This also makes handling such micro-quantities all the more difficult.

The new micro balances have an optional climate sensor module implemented in the draft shield, enabling you to have the temperature, humidity and barometric pressure under control at all times.

In our wide range of accessories, we also offer an ionizer to reduce the effects of static electricity.

How to Achieve Optimal Weighing Performance

The more confident you are in operating the balance and controlling environmental effects to prevent inaccuracy, the better your balance will...

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YAPP16 Dosing Q-App for Pharma Applications

Standards of defined concentrations are used to determine the concentration of unknown samples. Such standards need to be prepared accurately in order to minimize errors during analysis of unknown samples. However, it is next to impossible to weigh a solid sample so precisely that you can use a predefined volume of solvent. With the new YAPP16 Dosing Q-App software installed, your Cubis® MSA balance converts into an automated system for gravimetric monitoring of all measured values.

The Dosing Q-App automatically adjusts the volume of the solvent to the weight of your compound and determines the verified final concentration of your standard solution based on the weight of solvent actually added. Time-consuming and error-prone manual preparation of standards using volumetric determination is now a thing of the past.

For more information on YAPP16, visit our Cubis® App Center.

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Modules Available and Specifications

Weighing Module66S66P36S36P116P
Weighing Capacity | g6112|61316|3112|111
Readability | µg11|1011|102|10
Repeatability | ±µg4/1,5
(50g/2g)
10/2
(50g/2g)
2/1,5
(20g/1g)
8/1,5
(20g/1g)
10/4
(100g/5g)
Optimal Minimum Weight* | mg0,820,820,820,821,64
Typical Stabilization Time | s3.53.53.53.53.5
Typical Response | s1010101010
Off-center Loading | ±µg20 (20g)20 (20g)15 (10g)15 (10g)30 (50g)
Linearity | ±µg2020151520

Balances with weighing modules 66S, 66P, 36S and 36P are available with a choice of an MSA or an MSU display unit.

The 116P weighing module is available exclusively with the MSA touch-screen display and control unit for extended functionalities.

This model includes the YAPP16 Dosing Q-App as standard.

All models feature

  • An electronic leveling bubble displayed for fast and easy manual leveling guided by software
  • Choice of one of the following test reports:
    • 00 = Standard report as proof of compliance with specifications
    • TR = As for 00, but with a detailed test report showing specific measurement data
    • CE = Verified at the factory for use in legal metrology; with a European type approval certificate
  • DH draft shield: The DH draft shield is an automatic, motorized draft shield with a learning capability and a choice of operation either by an ergonomic, palm-activated key or by the touch-free infrared sensor 

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*According to USP (United States Pharmacopeia) Chapter 41, the optimal operating range is defined from 820d to maximum weighing capacity. That means the optimal minimum weight is 820d. Depending on the installation location and environmental conditions, this value may be higher.