Octet Systems Software

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Data Acquisition and Analysis Made Simple

Enables Easy Method Development and Data Analysis

  • Analysis of multiple sample plates - Software allows for the analysis of multiple sample plates and experiments together in Octet Data Analysis HT software, reducing analysis time from hours to minutes.
  • Data processing flexibility; customizable PDF data reports - More flexible and advanced data processing and correction options to choose from. PDF data reports can be customized using text, graphs, data tables and images.
  • Automated analysis - Automated analysis is enabled for quantitation, kinetic, and epitope binning data.
  • 21 CFR Part 11 compliance & electronic signatures - Primary data integrity is secured through electronic signatures—acquired data is digitally signed and is invalidated if tampered with.
  • 21 CFR Part 11 compliance with enhanced audit trail - All actions are recorded and time-stamped with details of old vs. new values.

Octet CFR software and our GxP Server enable data acquisition and data analysis in laboratories working under GMP, GLP, and 21 CFR Part 11 regulations. It also provides all necessary technical administrative features for compliance with FDA regulations. A Software Validation Package that verifies calculations is available.

Octet System Software
Design and Analyze an Assay in Minutes

A new assay can be set up in just a few minutes. To make assay setup even faster, experimental method templates are available. Analysis settings can be saved and applied to a new assay to significantly speed up routine analysis.

Compliance

Octet CFR Software and our GxP Server enable data acquisition and data analysis in laboratories working under GMP, GLP, and 21 CFR Part 11 regulations. It also provides all necessary technical administrative features for compliance with FDA regulations. Controlled access with multiple user levels and a set of permission structure are available: administrator, developer, supervisor, lab user.

Customized Report Generation

Create customized reports for experiments, combining various data elements such as graphs, text, data tables, company logo, images and experimental details. Reports are ready to be uploaded to an electronic notebook or stored in the database. Report templates can be saved and reloaded to make similar reports for additional datasets.

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Applications

Kinetics Assays

For analysis of assays including ligand/target binding, kinetic screening, kinetic analysis of protein-protein, protein-small molecules, antibody-antigen, antibody-VLP, antibody-Fc gamma receptors, and antibody-neonatal receptor (FcRn) interactions. Lot release and stability testing of drug molecules can also be analyzed using Octet software.

Additional features allow users to combine and analyze multiple experiments and plates together and employ flexible reference sample and biosensor subtraction.  Advanced data processing options can remove bulk shifts or assay artifacts.  Faster and improved 1:1, 1:2, 2:1 and mass transport curve fitting models along with Local (partial or full) or Global data fitting options.  Customize and export final reports in Excel and PDF.

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Quantitation Assays

Quantitation of total IgG, Fab and custom proteins, contaminant testing such as host cell protein (HCP) and residual protein A, pharmacokinetic (PK) assays, antibody isotyping in complex samples, glycosylation profiling, vaccine titer determination etc. Combine and analyze multiple experiments and plates together. Multiple and flexible reference subtraction Linear, 4 and 5-parameter logistic (PL) unweighted and weighted fittings. View and analyze any step(s) in a multi-step ELISA-type assay. Automated sample alert tools to evaluate data quality for precision, accuracy and dilution linearity, enabling you to interpret results with confidence.

Import previously made standard curves for routine assays Customize and export final reports in Microsoft® Excel® and PDF formats.

Epitope Binning Assays - Advanced Analysis with HT Software

Append and overlay data from multiple experiments, plates or biosensor trays to create a combined dataset for advanced analyses. Software automatically finds the binning cycle pattern and creates a 2-D traffic-light matrix and BinChart for you. Cluster antibodies in similar bins or groups using custom (Euclidean, Pearson, Maximum) algorithms. Additional matrix analyses like normalizing to controls or self-binding and highlighting unidirectional binning pairs can be performed. Simple data quality assessment can be accomplished by monitoring loading levels and flagging antibodies with high off-rates. Customize and export final reports in Excel and PDF.

Read Application Note

Specifications

Processor

3.0 GHz Quad Core processor or greater

Operating system

Windows 7 Professional or Windows 10 Professional, 64-bit.
Older Octet instruments are also compatible with Windows 7 Professional 32-bit. Contact a representative to learn more

Data connection

3 available USB 2.0 ports
Octet control features do not support USB 3.0
1 available RS-232 serial port - Two serial ports are required in some older Octet models, contact a representative to learn more

Memory

4 GB RAM or greater

Graphics display

Monitor with 1920x1080 resolution or better

Software installation and activation

A DVD or CD drive is required to install the Data Acquisition and Analysis software

Hard Disk

250 GB hard drive or greater 200 MB available hard disk space required for application files more to acquire data – a single experiment can range from 1 MB to over 100 MB

Additional Software

Microsoft Office

Helpful Tips

  • Laptops are not recommended for use with Data Acquisition
  • A DVD or CD drive is required to install the Data Acquisition and Analysis software
  • Computer workstations that are not supplied by Sartorius are not covered under the Octet warranty or service contracts.

Resources and applications on Octet Systems Software

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