Octet® QKe 8-Channel System Has Been Discontinued.

The Octet® QKe has been replaced by the Octet® R4 Protein Analysis System.

Explore the New Octet® R Series


Bio-Layer Interferometry (BLI) based on fiber optic biosensors

Sample volume

180–220 µL/well
Nondestructive testing, easily recovered

Data presentation

Sensorgrams displaying kinetic traces or concentration binding rates
Epitope binning and cross-blocking matrices and trace overlays
Tabulated kinetic or concentration data


Up to 8 assays in parallel; up to 96 assays per 96-well plate

Orbital flow capacity

Static or 100–1500 rpm

Analysis temperature

Ambient + 4°C to 40°C, in 1°C increments

Association rate constant (ka)

102 to 105  M-1 s-1

Dissociation rate constant (kd)

10-5 to 10-2  s-1

Affinity constant (KD)

0.1 mM to 0.1 nM

Baseline noise (RMS)

≤ 8 pm

Baseline drift

< 0.1 nm/hour

Quantitation range

1 µg/mL to 700 µg/mL at low rpm, LOD of 0.05 µg/mL at 1000 rpm

Quantitation precision



54 lb (24.5 kg)

Dimensions (H x W x D)

18.6 in (H) x 17 in (D) x 20.8 in (W)
47 cm (H) x 43 cm (D) x 53 cm (W)

Sample type

Proteins, antibodies, peptides, serum containing media (up to 25%), DMSO containing buffers, virus-like particles, untreated cell culture supernatants and crude cell lysates

Sample plate

Standard, 96-well, black, flat-bottom microplate

Molecular weight detection

>5000 Da

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