Octet® R Series: Label-Free Biomolecular Interaction Analysis

Accelerate Your Research with a Field-Upgradeable, Label-Free Biomolecule Analysis Platform

Tackle analytical complexity with the all new Octet® R series. These new systems leverage our label-free Octet® BLI technology that maximizes application versatility. With three different models to choose from, users can strike the right balance between throughput needs and budget.

Discover the Octet® R Series

All models in the Octet® R series have comparable sensitivity and direct detection of specific proteins or drug molecules - even in complex mixtures and unpurified samples like cell culture supernatants and lysates.  The Octet® R series is ideal for academic start-up and low volume labs that are looking for high-quality, label-free capabilities without compromising on assay sensitivity.

Whether your lab is just getting started or requires higher throughput for screenings or analyzing large numbers of samples, the Octet® R series has a range of price points and throughput capabilities to help you simplify progress. 

The Octet® BLI is an easy-to use, real-time analytical tool that rapidly screens critical quality attributes.

2-Channel System: Octet® R2

Grows With Your Biomolecule Characterization Needs

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Octet R4 label free detection system

4-Channel System: Octet® R4

The Perfect Balance Between Cost and Throughput with Given Leeway

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8-Channel System: Octet® R8

Unmatched Flexibility and Versatility in Protein Analysis

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Benefits of Choosing the Octet® R Series


Address a broad range of ligand-binding assays - from protein quantitation to impurity testing to kinetics characterization of biotherapeutic medicines  on one fluidic-free, low-maintenance platform. 


Easily transition between biologics development or drug discovery workflow steps, from basic research to lead optimization to GMP manufacturing. Octet® R series offers throughput, crude sample compatibility, and GxP-compliance packages suitable for every stage.


Futureproof your research while protecting your investment. The Octet® R2 and R4 are field-upgradeable within a single service visit. Increase your throughput and speed of decision-making without the hassle of downtime or system trade-in.

Therapeutic proteins, monoclonal antibodies (mAbs), bispecific antibodies (bsAbs), and antibody-drug conjugates (ADCs) are all large complex molecules that require reliable in-depth characterization and robust concentration determination of the active analyte or impurities such as host cell protein (HCP). On the other hand, screening and characterizing small drug molecules is equally important. Octet® Bio-Layer Interferometry (BLI) systems offer an advanced, fast, robust and fluidics-free approach for protein-protein and protein-small molecule analysis.

The Octet® portfolio’s newest offering - the Octet® R series - consists of three different configurations so you can balance your throughput needs and budget.  Along with high sensitivity and performance, this new series offers field upgradeability for maximum flexibility and future proofing of your investment. Increase your system's throughput when YOU need it.

Featured Resources

Case Study

Bispecific Antibodies: From Research to Clinical Application

Learn how Octet BLI transforms our approach to drug discovery and development

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Learn More About the Octet® R Series

Octet top 10 reasons to choose BLI

Top Ten Reasons to Choose Sartorius Octet®️ BLI Technology to Accelerate Your Research, Development, and Manufacturing

PDF | 167.1 KB
Octet R2 datasheet cover

Octet® R2 System Datasheet

PDF | 681.8 KB

Octet® R4 System Datasheet

PDF | 912.4 KB

Octet® R8 System Datasheet

PDF | 1.2 MB

New Octet®️ R Series of Systems Flyer

PDF | 523.8 KB
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Octet® BLI Infographic

PDF | 6.1 MB

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