Anti-Mouse IgG Fc Capture (AMC) Biosensors
For Immobilization and Subsequent Kinetic Characterization of Mouse IgGs and other Fc-Containing Proteins
- Complete kinetic analysis (ka, kd, KD) between mouse Fc-containing proteins and target analytes
- Off-rate ranking of hybridoma and stable cell-line supernatants
- Epitope binning/mapping (from crude or purified samples)
Anti-Mouse IgG Fc Capture (AMC) biosensors enable kinetic characterization of macromolecular interactions between mouse Fc-containing proteins and target analytes.
Immobilization of mouse Fc-containing proteins is achieved through a factory immobilized anti-mouse Fc-specific antibody whose high-affinity for the mouse Fc domain provides the stable baseline required for demanding kinetics applications. AMC biosensors can be regenerated up to 10 times via a standard low-pH protocol in as little as two minutes for select applications.