Octet® ProA Biosensors

For Determination of Antibody Concentration

  • Direct measurement of immunoglobulins (IgG)
  • Assay samples without centrifugation
  • Fast turnaround of results
  • Broad dynamic range
  • Correlates to HPLC
  • Direct measurement of immunoglobulins (IgG) 25ng – 2mg/mL

Octet® ProA biosensors are coated with Protein A and enable rapid antibody quantitation from crude lysates, cell culture supernatants and complex matrices. The direct quantitation assay format of the Octet® ProA biosensors provides ELISA data in less than 2 minutes and can be automated for high throughput screening efforts. Using an established pH-based regeneration protocol, the biosensors can be regenerated multiple times to provide a cost-effective and time-saving assay format.

Octet® ProA Biosensors

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Featured Resources

Application Note

MAb Quantitation Protein A HPLC vs Protein A Bio-Layer Interferometry

Rapid, accurate and cost-effective quantitation of monoclonal antibodies (MAbs) is essential for bioprocessing.

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Application Note

Quantitation of Fc-Fusion Protein in Cell Culture Supernatants

The cell line development group at Biogen IDEC needed a robust assay for the measurement of Fc-fusion protein in crude cell culture supernatants.

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Enhanced Efficiency in Lot Release and In-Process Testing of Biologics cover
White Paper

Enhanced Productivity and Labor Efficiency

In Lot Release and In-Process Testing of Biologics in GxP Laboratories

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Additional Resources 

selection guide
Flyer

Octet® BLI Biosensor Selection Guide

PDF | 404.8 KB
Octet® Protein A Biosensors for Determination of Antibody Concentration
Datasheet

Octet® Protein A Biosensors for Determination of Antibody Concentration

PDF | 492.6 KB

Poster: Dynamic Binding Capacity Of Resins Using Biolayer Interferometry

PDF | 231.5 KB
High Throughput Bio-Layer Interferometry in Therapeutic Antibody Discovery and Development

High Throughput Bio-Layer Interferometry in Therapeutic Antibody Discovery and Development

PDF | 456.1 KB
app note cover
Application Note

CaptureSelect Affinity Ligands For Antibody Detection And Characterization

PDF | 1.3 MB
A Fast and High Precision Influenza Vaccine Potency Assay
Application Note

A Fast and High Precision Influenza Vaccine Potency Assay

PDF | 687.7 KB
application note thumbnail
Application Note

Fast Quantitation of Proteins and Antibodies Using the Octet® N1 System

PDF | 350.2 KB
Residual Protein A Detection Kit
Technical Note

Residual Protein A Detection Kit

PDF | 1.8 MB

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