BioPAT® MODDE

  • Optimization of growth and production culture media in ambr™ bioreactors
  • Screening and optimization of basic process state variables with BIOSTAT® multi-bioreactor systems
  • Optimization of purification conditions with Sartobind® technology
  • Robustness studies of cross-flow filtration conditions with SARTOFLOW® systems
  • Optimization of freeze and thaw rates with Celsius® systems
  • Design space estimation (DSE) and validation

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BioPAT® MODDE is a state-of-the-art DoE software package that is used by scientists, engineers and statisticians alike to help understand complex processes and products.

BioPAT® MODDE enables fast and effective identification of critical process parameters (CPPs) and, subsequently, establishment of a Design Space, resulting in reduced bioprocess complexity and increased process understanding. This, in turn, facilitates process transfers.

The Design Space tools provided by BioPAT® MODDE present a region of operability that meets risk analysis specifications and that guides engineers in determining how likely it is that their experiments will truly identify the most reliable operating region.

Minimum System Requirements

Screen Resolution1024 x 768 color display
Graphics Card3-D acceleration and OpenGL support
BrowserInternet Explorer version 6 or later
Operating SystemWindows® 7 or 8


Demo Version

The demo will work for 30 days after the first installation and cannot be reinstalled on the same computer. Copy, Paste, Print, the Report Generator, and the COM-interface in the demo are disabled. All other functionality is available.

Full Version and Upgrade Version from BioPAT® MODDE 10

BioPAT® MODDE requires an activation key that is 20 characters long (e.g. ABC12-EFGHI-34JKL-MN56O).

Full Version for use with BioPAT® MFCS/win

BioPAT® MODDE requires an activation key that is 20 characters long (e.g. ABC12-EFGHI-34JKL-MN56O).

Literature


Introduction to DoE and BioPAT® MODDE

Basic tutorials that describe the use of BioPAT® MODDE in screening and optimization.

Robustness test and QbD

An introduction to Design Space validation and estimation. BioPAT® MODDE introduces an excellent toolbox for validation and defining the best region for performance.

Rectangular designs for multi unit platforms

BioPAT® MODDE has an excellent tool for setting up smart designs when using MUP’s for HTS or optimization. This tutorial describes the procedure for design construction and evaluation.

Mixture designs for multi unit platforms

BioPAT® MODDE has an excellent tool for setting up smart designs when using MUP’s for HTS or optimization. This tutorial describes the procedure for design construction and evaluation.

D-Optimal designs

BioPAT® MODDE has the power to construct designs with several types of constraints. The tutorial is an introduction to construction of D-Optimal designs.