Affinity versus Avidity: Differentiating Between Binding Phenomena Webinar
Last updated: September 2023
To choose the best lead candidates during drug and antibody screening, scientists characterize a molecule’s binding properties, such as kinetics and affinity. Robust assay design reduces experimental artifacts caused by avidity and enables researchers to determine binding kinetics and affinity values. Understanding the differences between affinity and avidity is essential when designing and developing kinetic binding assays.
In this webinar, Tim Heiseler - Senior Application Scientist at Sartorius - discusses the phenomena of affinity and avidity as measured in label-free biomolecular interaction analysis and explain how to recognize and resolve problems arising from interactions that contain bivalent or multivalent molecules.
- Document type: Webinar
- View time: 26 minutes
- Clarifying and demonstrating binding affinity and avidity
- Identifying multivalent analyte interactions and assay design considerations
- Optimizing assays to avoid artifacts in biomolecular interaction analysis
- Introducing ChromoTek’s nanobodies and the Spot-Tag® system
Tim Heiseler, PhD
Senior Application Scientist