Application Note: Ultrapure Water for Trace Analysis
Authors: Rüdiger Wittlake, Dr. Petra Slabizki, Hans-Thomas Herbst, Carsten Röttger, Dr. Elmar Herbig | Last updated: November 2020
Overview
The quality of the solvents, especially water, is a critical factor for achieving consistent and interference-free results in liquid chromatography, as well as for the method's sensitivity, particularly when it comes to trace analysis applications. The following application note compares different sources of ultrapure water used as an eluent in high-performance liquid chromatography with diode array detection (HPLC-DAD) and mass spectrometry (MS) systems in various experiments.
- Document type: Application Note
- Page count: 9
- Read time: 12 minutes
Key Takeaways
- Arium® Mini Plus water is highly suitable for use in chromatography and mass spectrometry
- Arium® Mini Plus water achieves a low background signal, improving analytical sensitivity and reliability
- Freshly purified water is cost-effective and eliminates contamination from open bottles
- Using water that has been freshly purified helps prevent problems like the leaching of sodium ions from glass bottles, which can compromise the sensitivity of LC-MS, an issue that arises when water is stored in glass bottles for extended durations
This Resource is Designed for:
- Lab Researchers
- Lab Technicians
- Analytical Lab
- Quality Control or Validation Lab
- Forensic Scientists
- Environmental Scientist
- Food Scientists
- Regulatory Affairs Specialists
- Academics and Students
Applications Supported:
- Life Science Research
- Water Purification
- Liquid Chromatography (LC)
- Total Organic Carbon (TOC)
- Mass Spectrometry (MS)
- High-Performance Liquid Chromatography with Diode Array Detection (HPLC-DAD)
- Ultrapure Water
- ASTM Type 1 Water
- Arium® Mini Plus
